Nicholas V. Hud

Nicholas V. Hud
nick.hud@chemistry.gatech.edu

Nicholas Hud was born and raised in Los Angeles, California. He received his B.S. degree in physics from Loyola Marymount University. His Ph.D. was conferred by the University of California, Davis for physical investigations of DNA condensation by protamine. From 1992-1995 he was a postdoctoral fellow in the biology and biotechnology research program at Lawrence Livermore National Laboratory with Rod Balhorn. From 1995-1998 he was an NIH postdoctoral fellow in the Molecular Biology Institute at UCLA where he worked with Juli Feigon and Frank A. L. Anet on the application of NMR spectroscopy to the study of DNA-cation interactions. Hud joined the faculty at Georgia Tech as an assistant professor in 1999 and was promoted to full professor in 2008. He has been visiting professor of chemistry at the National NMR Center in Slovenia, and at Imperial College London. Hud currently serves as PI of the NSF Center for Chemical Evolution, as chair of the biochemistry division of the School of Chemistry and Biochemistry, as co-director of the Georgia Tech-Emory University Center for Fundamental and Applied Molecular Evolution (FAME), and as associate director of the Petit Institute for Bioengineering and Bioscience.

Associate Director, Parker H. Petit Institute for Bioengineering and Bioscience
Regents’ Professor of Chemistry & Biochemistry
Director, NSF Center for Chemical Evolution
Phone
404-385-1162
Office
Petit Biotechnology Building, Office 1108
Additional Research
Intercalation-mediated Nucleic Acid Assembly, The Molecular Midwife & the Origin of Life, Nucleic Acid-Cation Interactions, Understanding DNA & RNA Condensation. The research in our laboratory is directed towards elucidating the fundamental chemical and physical principles that govern nucleic acid (RNA and DNA) assembly. We are interested in how the physical properties of nucleic acids govern biological functions in contemporary life, and how these same properties provide clues to the origin and early evolution of life. We are also applying our knowledge of nucleic acids to problems that are of current importance in medicine and biotechnology. Specific projects include investigations of: 1) the origin and evolution of RNA; 2) cation, solvent and small molecule interactions with nucleic acids; 3) nucleic acid condensation and packaging; and 4) folding and evolution of the ribosome. Our research involves the application of a wide variety of physical and chemical techniques.
IRI and Role
Bioengineering and Bioscience > Leadership, Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Chemistry & Biochemistry

Ching-Hua Huang, Ph.D.

Ching-Hua Huang, Ph.D.
ching-hua.huang@ce.gatech.edu

Ching-Hua Huang, Ph.D., is the Turnipseed Family Chair and Professor in the School of Civil and Environmental Engineering at Georgia Institute of Technology. Huang received her Ph.D. and M.S. degrees in environmental engineering from Johns Hopkins University. Huang’s expertise includes environmental chemistry, advanced water/wastewater treatment technology, contaminants of emerging concern, sustainable water reuse, waste remediation and resource recovery. Huang has supervised many research projects sponsored by various agencies, and has published more than 170 peer-reviewed journal papers, book chapters and conference proceeding papers. She is the Associate Editor of the American Chemical Society's Environmental Science & Technology Water and the Editorial Advisory Board member of Environmental Science & Technology. 

Turnipseed Family Chair and Professor
Phone
404.893.7694
Office
School of Civil and Environmental Engineering
IRI and Role
Bioengineering and Bioscience > Faculty
Energy > Faculty
Energy > Research Community
Sustainable Systems
Bioengineering and Bioscience
Energy
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > School of Civil and Environmental Engineering
Research Areas
Sustainable Systems
  • Resource and Materials Use

Yuhang Hu

Yuhang Hu
yuhang.hu@me.gatech.edu

Dr. Yuhang Hu Joined the Woodruff School of Mechanical Engineering and the School of Chemical and Biomolecular Engineering at Georgia Institute of Technology as an assistant professor in August 2018. Prior to that, Dr. Hu was an assistant professor in the Department of Mechanical Science and Engineering at University of Illinois at Urbana-Champaign from 2015 to 2018. She received her Ph.D. from Harvard University in the area of Solid Mechanics. She worked in the area of Materials Chemistry as a post-doctoral fellow at Harvard from 2011 to 2014.

Associate Professor, Mechanical Engineering and Chemical and Biomolecular Engineering
Phone
404-894-2555
Office
MRDC 4107
Additional Research

Our study focuses on Soft Active Materials especially those consisting both solid and liquid, such as gels, cells and soft biological tissues. Our research is at the interface between mechanics and materials chemistry. Our studies span from fundamental mechanics to novel applications.

IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
Matter and Systems > Affiliated Faculty
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering
Research Areas
Matter and Systems
  • Human-Centric Technologies
  • Computing and Communication Technologies

David Hu

David Hu
hu@me.gatech.edu

David Hu is a fluid dynamicist with expertise in the mechanics of interfaces between fluids such as air and water. He is a leading researcher in the biomechanics of animal locomotion. The study of flying, swimming and running dates back hundreds of years, and has since been shown to be an enduring and rich subject, linking areas as diverse as mechanical engineering, mathematics and neuroscience. Hu's work in this area has the potential to impact robotics research. Before robots can interact with humans, aid in minimally-invasive surgery, perform interplanetary exploration or lead search-and-rescue operations, we will need a fundamental physical understanding of how related tasks are accomplished in their biological counterparts. Hu's work in these areas has generated broad interest across the fields of engineering, biology and robotics, resulting in over 30 publications, including a number in high-impact interdisciplinary journals such as Nature, Nature Materials, Proceedings of the National Academy of Sciences as well as popular journals such as Physics Today and American Scientist. Hu is on editorial board member for Nature Scientific Reports, The Journal of Experimental Biology, and NYU Abu Dhabi's Center for Center for Creative Design of Materials. He has won the NSF CAREER award, Lockheed Inspirational Young Faculty award, and best paper awards from SAIC, Sigma Xi, ASME, as well as awards for science education such as the Pineapple Science Prize and the Ig Nobel Prize. Over the years, Hu's research has also played a role in educating the public in science and engineering. He has been an invited guest on numerous television and radio shows to discuss his research, including Good Morning America, National Public Radio, The Weather Channel, and Discovery Channel. His ant research was featured on the cover of the Washington Post in 2011. His work has also been featured in The Economist, The New York Times, National Geographic, Popular Science and Discover His laboratory appeared on 3D TV as part of a nature documentary by 3DigitalVision, "Fire ants: the invincible army," available on Netflix.

Professor, George W. Woodruff School of Mechanical Engineering
Professor, School of Biology
Director, Hu Lab for Biolocomotion
Phone
404.894.0573
Office
LOVE 124
Additional Research

Fluid Mechanics: Fluid dynamics, solid mechanics, biomechanics, animal locomotion, and physical applied mathematics. Dr. David Hu's research focuses on fundamental problems of hydrodynamics and elasticity that have bearing on problems in biology. He is interested in the dynamics of interfaces, specifically those associated with fluid-solid and solid-solid interactions. The techniques used in his work include theory, computation, and experiment. He is also interested in pursuing biomimetic technologies based on nature's designs.

IRI and Role
Bioengineering and Bioscience > Faculty
Robotics > Core Faculty
Robotics
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Scott Hollister

Scott Hollister
scott.hollister@bme.gatech.edu

I am the Patsy and Alan Dorris Chair of Pediatric Technology and Professor of Biomedical Engineering at the Georgia Institute of Technology. I also direct the Center for 3D Medical Fabrication (3DMedFab) and the Tissue Engineering and Mechanics Laboratory at Georgia Tech. We develop a range of 3D printed medical devices. We have over 25 devices implanted in patients for treatment of trachecobronchomalacia.

Professor and Patsy and Alan Dorris Chair in Pediatric Technology
Phone
404-385-5506
Office
UAW 2102
Additional Research
My research interests focus on image-based computational design and 3D biomaterial printing for patient specific devices and regenerative medicine, with specific interests in pediatric applications.Clinical application interests include airway reconstruction and tissue engineering, structural heart defects, craniofacial and facial plastics, orthopaedics, and gastrointestinal reconstruction.We specifically utilize patient image data as a foundation to for multiscale design of devices, reconstructive implants and regenerative medicine porous scaffolds.We are also interested in multiscale computational simulation of how devices and implants mechanically interact with patient designs, combining these simulations with experimental measures of tissue mechanics.We then transfer these designs to both laser sintering and nozzle based platforms to build devices from a wide range of biomaterials. Subsequently, we are interested in combining these 3D printed biomaterial platforms with biologics for patient specific regenerative medicine solutions to tissue reconstruction. 
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering

Josiah Hester

Josiah Hester
josiah@gatech.edu

Josiah Hester works broadly in computer engineering, with a special focus on wearable devices, edge computing, and cyber-physical systems. His Ph.D. work focused on energy harvesting and battery-free devices that failed intermittentently. He now focuses on sustainable approaches to computing, via designing health wearables, interactive devices, and large-scale sensing for conservation. 
   
His work in health is focused on increasing accessibility and lowering the burden of getting preventive and acute healthcare. In both situations, he designs low-burden, high-fidelity wearable devices that monitor aspects of physiology and behavior, and use machine learning techniques to suggest or deliver adaptive and in-situ interventions ranging from pharmacological to behavioral. 
   
His work is supported by multiple grants from the NSF, NIH, and DARPA. He was named a Sloan Fellow in Computer Science and won his NSF CAREER in 2022. He was named one of Popular Science's Brilliant Ten, won the American Indian Science and Engineering Society Most Promising Scientist/Engineer Award, and the 3M Non-tenured Faculty Award in 2021. His work has been featured in the Wall Street Journal, Scientific American, BBC, Popular Science, Communications of the ACM, and the Guinness Book of World Records, among many others.

Interim Associate Director for Community-Engaged Research
Catherine M. and James E. Allchin Early Career Professor
Professor
Director, Ka Moamoa – Ubiquitous and Mobile Computing Lab
BBISS Lead: Computational Sustainability
Office
TSRB 246
IRI and Role
Sustainable Systems > Initiative Lead
Sustainable Systems > Staff
Bioengineering and Bioscience > Faculty
Matter and Systems > Affiliated Faculty
Bioengineering and Bioscience
Data Engineering and Science > Faculty
University, College, and School/Department
Georgia Institute of Technology > College of Computing > School of Interactive Computing
Research Areas
Sustainable Systems
  • Ecosystem and Environmental Health
  • Global Sustainable Development
Matter and Systems
  • Human-Centric Technologies

Peter Hesketh

Peter Hesketh
peter.hesketh@me.gatech.edu

Peter Hesketh came to Georgia Tech in spring 2000 as a professor in the George W. Woodruff School of Mechanical Engineering. Prior, he was associate professor at the University of Illinois at Chicago. Hesketh's research interests involve sensors and micro/nano-electro-mechanical Systems (MEMS/NEMS). Many sensors are built by micro/nanofabrication techniques and this provides a host of advantages including lower power consumption, small size and light weight. The issue of manipulation of the sample in addition to introduce it to the chemical sensor array is often achieved with microfluidics technology. Combining photolithographic processes to define three-dimensional structures can accomplish the necessary fluid handling, mixing, and separation through chromatography. Hesketh is also interested in nanosensors, impedance based sensors, miniature magnetic actuators and the use of stereolithography for sensor packaging. He has published over sixty papers and edited fifteen books on microsensor systems.

Professor, Woodruff School of Mechanical Engineering
Phone
404.894.8496
Office
Love 317
Additional Research

Microfabrication; micromachining; sensors and actuators; biosensors; "Dr. Hesketh's research interests are in Sensors and Micro/Nano-electro-mechanical Systems (MEMS/NEMS).Many sensors are built by micro/nanofabrication techniques and this provides a host of advantages including lower power consumption, small size and light weight.The issue of manipulation of the sample in addition to introduce it to the chemical sensor array is often achieved with microfluidics technology.Combining photolithographic processes to define three-dimensional structures can accomplish the necessary fluid handling, mixing, and separation through chromatography.For example, demonstration of miniature gas chromatographyand liquid chromatography with micromachined separation columns demonstrates how miniaturization of chemical analytical methods reduces the separation time so that it is short enough, to consider the measurementequivalentto ""read-time"" sensing. A second focus area is biosensing. Professor Hesketh has worked on a number of biomedical sensors projects, including microdialysis for subcutaneous sampling, glucose sensors, and DNA sensors. Magnetic beads are being investigated as a means to transport and concentrate a target at a biosensor interface in a microfluidic format, in collaboration with scientists at the CDC. His research interests also include nanosensors, nanowire assembly by dielectrophoresis; impedance based sensors, miniature magnetic actuators; use of stereolithography for sensor packaging. He has published over sixty papers and edited fifteen books on microsensor systems."

IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Katherine Hekman, M.D., Ph.D.

Katherine Hekman, M.D., Ph.D.
khekman@emory.edu

Dr. Hekman completed her BA in Biophysics and Spanish Literature at Johns Hopkins. She then chose to pursue medicine and completed her MD and PhD in Molecular Medicine at the University of Chicago, where she found Vascular Surgery. She completed her Vascular Surgery Integrated Residency at Northwestern University, including a post-doctoral research fellowship in the lab of Dr. Jason Wertheim, MD, PhD. There she discovered the role of autophagy in the longevity and health of endothelial cells derived from induced pluripotent stem cells. She joined faculty in Vascular Surgery at Emory and the Atlanta VA Healthcare System in 2021, where her lab focuses on generating patient-specific induced pluripotent stem cell-derived endothelial cells to produce personalized regenerative therapies for vascular disease.

Assistant Professor
Phone
619-754-5405
Office
1365 Clifton Rd NE; Atlanta, GA 30322
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University > Department of Surgery

Christine Heitsch

Christine Heitsch
heitsch@math.gatech.edu

Christine Heitsch is Professor of Mathematics at Georgia Tech, with courtesy appointments in Biological Sciences and Computational Science & Engineering as well as an affiliation with the Petit Institute for Bioengineering & Bioscience.

She is also Director of the new Southeast Center for Mathematics and Biology (SCMB), an NSF-Simons MathBioSys Research Center, and finishing her tenure directing the GT Interdisciplinary Mathematics Preparation and Career Training (IMPACT) Postdoctoral Program.

Heitsch's research interests lie at the interface between discrete mathematics and molecular biology, specifically combinatorial problems "as motivated by" and "with applications to" fundamental biomedical questions like RNA folding.

Students interested in pursuing graduate studies in discrete mathematical biology can do so through a number of GT PhD programs including Bioinformatics or Quantitative Biosciences as well as Algorithms, Combinatorics, and Optimization (ACO), Computational Science & Engineering (CSE), and (of course) Mathematics.
 

Professor
Phone
404-894-4758
Office
Skiles 211B
Additional Research
Heitsch's research interests lie at the interface between discrete mathematics and molecular biology, specifically combinatorial problems "as motivated by" and "with applications to" fundamental biomedical questions like RNA folding.
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Mathematics

Karmella Haynes

Karmella Haynes
karmella.ann.haynes@emory.edu

Many people are familiar with “genetics,” the inheritance of visible traits like eye and hair color. Traits are encoded by a molecular alphabet (A,T,C,G) in the well known double helix structure, DNA. Less well known, but quickly gaining attention, is the network of protein particles that interact with DNA to control the folding of chromosomes and the expression of inherited traits. This process is epi-genetics (epi, EH-pee = upon or above). Our research group uses gene and protein engineering to create new epigenetic machinery that regulates DNA at will. One day synthetic epigenetics may allow us to rationally design new biological systems with predictable, reliable behavior and replace “magic bullet medicine” with “smart medicine.”

We assemble interchangeable protein modules to build synthetic transcription factors that regulate gene activity in human cells. Unlike typical synthetic transcription factors that recognize specific DNA sequences, our Polycomb-based transcription factors (“PcTFs”) are engineered to read chromatin modifications. Thus, a single engineered TF could activate a group of silenced, therapeutic genes in cancer cells. Using strong gene activators could enhance cancer treatment and advance epigenetic medicine.

As synthetic biologists, our goal is to make the folded DNA-protein material, or chromatin (KRO-mah-tin = dark colored material in the nucleus of a fixed and stained cell), easier to design and engineer. Groups of genes often reside in the same compartments, and share the same DNA-protein packaging structures. Therefore, a small artificial change in one packaging protein can reprogram the expression of dozens, and even hundreds of genes. Is this outcome messy and useless, or is it a powerful mode of signal amplification that changes cells in useful ways? To answer this question, our group couples synthetic biology with bioinformatics by interrogating the expression of thousands of genes after we introduce artificial chromatin proteins into cells.

Assistant Professor
Phone
404.727.0531
Office
HSRB E154
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering