Peter Kasson

Peter Kasson
peter.kasson@chemistry.gatech.edu

Peter Kasson is an international leader in the study of biological membrane structure, dynamics, and fusion, with particular application to how viruses gain entry to cells. His group performs both high-level experimental and computational work – a powerful combination that is critical to advancing our understanding of this important problem. His publications describe inventive approaches to the measurement of viral fusion rates and characterization of fusion mechanisms, and to the modeling of large-scale biomolecular and lipid assemblies. He has applied these insights to the prediction of pandemic outbreaks and drug resistance, with particular attention to Zika, SARS-CoV-2, and influenza pathogens in recent years. See https://kassonlab.org/ for more information.

Professor of Chemistry and Biomedical Engineering
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Data Engineering and Science
Bioengineering and Bioscience

Lynn Kamerlin

Lynn Kamerlin
skamerlin3@gatech.edu

Lynn Kamerlin received her Master of Natural Sciences from the University of Birmingham (UK), in 2002, where she remained to complete a PhD in Theoretical Organic Chemistry under the supervision of Dr. John Wilkie (awarded 2005). Subsequently, she was a postdoctoral researcher in the labs of Stefan Boresch at the University of Vienna (2005-2007), Arieh Warshel at the University of Southern California (2007-2009, Research Associate at the University of Southern California in 2010) and Researcher with Fahmi Himo (2010). She is currently a Professor and Georgia Research Alliance – Vasser Wooley Chair of Molecular Design at Georgia Tech, a Professor of Structural Biology at Uppsala University, a Fellow of the Royal Society of Chemistry. She has also been a Wallenberg Scholar, the recipient of an ERC Starting Independent Researcher Grant (2012-2017) and the Chair of the Young Academy of Europe (YAE) in 2014-2015. Her non-scientific interests include languages (fluent in 5), amateur photography and playing the piano.

Professor
Fellow of the Royal Society of Chemistry
Phone
(404) 385-6682
Office
MoSE 2120A
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience

Christine Heitsch

Christine Heitsch
heitsch@math.gatech.edu

Christine Heitsch is Professor of Mathematics at Georgia Tech, with courtesy appointments in Biological Sciences and Computational Science & Engineering as well as an affiliation with the Petit Institute for Bioengineering & Bioscience.

She is also Director of the new Southeast Center for Mathematics and Biology (SCMB), an NSF-Simons MathBioSys Research Center, and finishing her tenure directing the GT Interdisciplinary Mathematics Preparation and Career Training (IMPACT) Postdoctoral Program.

Heitsch's research interests lie at the interface between discrete mathematics and molecular biology, specifically combinatorial problems "as motivated by" and "with applications to" fundamental biomedical questions like RNA folding.

Students interested in pursuing graduate studies in discrete mathematical biology can do so through a number of GT PhD programs including Bioinformatics or Quantitative Biosciences as well as Algorithms, Combinatorics, and Optimization (ACO), Computational Science & Engineering (CSE), and (of course) Mathematics.
 

Professor
Phone
404-894-4758
Office
Skiles 211B
Additional Research
Heitsch's research interests lie at the interface between discrete mathematics and molecular biology, specifically combinatorial problems "as motivated by" and "with applications to" fundamental biomedical questions like RNA folding.
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Mathematics

Daniel Goldman

Daniel Goldman
dgoldman3@gatech.edu

My research integrates my work in complex fluids and granular media and the biomechanics of locomotion of organisms and robots to address problems in nonequilibrium systems that involve interaction of matter with complex media. For example, how do organisms like lizards, crabs, and cockroaches cope with locomotion on complex terrestrial substrates (e.g. sand, bark, leaves, and grass). I seek to discover how biological locomotion on challenging terrain results from the nonlinear, many degree of freedom interaction of the musculoskeletal and nervous systems of organisms with materials with complex physical behavior. The study of novel biological and physical interactions with complex media can lead to the discovery of principles that govern the physics of the media. My approach is to integrate laboratory and field studies of organism biomechanics with systematic laboratory studies of physics of the substrates, as well as to create mathematical and physical (robot) models of both organism and substrate. Discovery of the principles of locomotion on such materials will enhance robot agility on such substrates

Dunn Family Professor; School of Physics
Director; Complex Rheology And Biomechanics (CRAB) Lab
Phone
404.894.0993
Office
Howey C202
Additional Research

biomechanics; neuromechanics; granular media; robotics; robophysics

IRI and Role
Bioengineering and Bioscience > Faculty
Robotics > Core Faculty
Robotics
Bioengineering and Bioscience
Matter and Systems > Affiliated Faculty
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Physics
Research Areas
Matter and Systems
  • Computing and Communication Technologies
  • Frontiers in Infrastructure

Greg Gibson

Greg Gibson
greg.gibson@biology.gatech.edu

Greg Gibson is Professor of Biology and Director of the Center for Integrative Genomics at Georgia Tech. He received his BSc majoring in Genetics from the University of Sydney (Australia) and PhD in Developmental Genetics from the University of Basel. After transitioning to quantitative genetic research as a Helen Hay Whitney post-doctoral fellow at Stanford University, he initiated a program of genomic research as a David and Lucille Packard Foundation Fellow at the University of Michigan. He joined the faculty at Georgia Tech in Fall of 2009, after ten years at North Carolina State University where he developed tools for quantitative gene expression profiling and genetic dissection of development in the fruitfly Drosophila. He is now collaborating with the Center for Health Discovery and Well Being on integrative genomic analyses of the cohort. Dr Gibson is an elected Fellow of the American Association for the Advancement of Science, and serves as Section Editor for Natural Variation for PLoS Genetics. He has authored a prominent text-book, a "Primer of Genome Science" as well as a popular book about genetics and human health, "It Takes a Genome".

Professor
Director, Center for Integrative Genomics
Adjunct Professor, School of Medicine, Emory University
Phone
404-385-2343
Office
EBB 2115A
Additional Research
Quantitative Evolutionary Genetics. After 15 years working on genomic approaches to complex traits in Drosophila, my group has spent much of the past 10 years focusing on human quantitative genetics. We start with the conviction that genotype-by-environment and genotype-by-genotype interactions are important influences at the individual level (even though they are almost impossible to detect at the population level). We use a combination of simulation studies and integrative genomics approaches to study phenomena such as cryptic genetic variation (context-dependent genetic effects) and canalization (evolved robustness) with the main focus currently on disease susceptibility.​ Immuno-Transcriptomics.As one of the early developers of statistical approaches to analysis of gene expression data, we have a long-term interest in applications of transcriptomics in ecology, evolution, and lately disease progression. Since blood is the mostaccessible human tissue, we've examined how variation is distributed within and among populations, across inflammatory and auto-immune states, and asked how it relates to variation in immune cell types. Our axes-of-variation framework provides a new way of monitoring lymphocyte, neutrophil, monocyte and reticulocyte profiles from whole peripheral blood. Most recently we have also been collaborating on numerous studies of specific tissues or purified cell types in relation to such diseases as malaria, inflammatory bowel disease, juvenile arthritis, lupus, and coronary artery disease. Predictive Health Genomics. Personalized genomic medicine can be divided into two domains: precision medicine and predictive health. We have been particularly interested in the latter, asking how environmental exposures and gene expression, metabolomic and microbial metagenomics profiles can be integrated with genomesequencing or genotyping to generate health risk assessments. A future direction is incorporation of electronic health records into genomic analyses of predictive health. Right now it is easier to predict the weather ten years in advance than loss of well-being, but we presume that preventative medicine is a big part of the future of healthcare.​
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Facundo Fernandez

Facundo Fernandez
facundo.fernandez@chemistry.gatech.edu

Facundo was born in Buenos Aires, Argentina. He received his MSc in Chemistry from the College of Exact and Natural Sciences, Buenos Aires University in 1995 and his PhD in Analytical Chemistry from the same University, in 1999.  In August 2000, he joined the research group of Prof. Richard N. Zare in the Department of Chemistry at Stanford University.  His work focused on several aspects of Hadamard transform time-of-flight mass spectrometry with an emphasis on coupling this technique to capillary-format separation methods.  In 2002, he joined the group of Prof. Vicki Wysocki in the Department of Chemistry at the University of Arizona, to develop novel tandem mass spectrometers for gas-phase peptide ion studies. In 2004 he joined the School of Chemistry and Biochemistry at the Georgia Institute of Technology where he currently holds the position of Vasser-Woolley Endowed Professor in Bioanalytical Chemistry and Associate Chair for Research and Graduate Training. He is the author of over 185 peer-reviewed publications and numerous invited presentations at national and international conferences. He has received several awards, including the NSF CAREER award, the CETL/BP Teaching award, the Ron A. Hites best paper award from the American Society for Mass Spectrometry, and the Beynon award from Rapid Communications in Mass Spectrometry, among others. He serves on the editorial board of The Analyst and as an Associate editor for the Journal of the American Society for Mass Spectrometry. His current research interests include the field of metabolomics and the development of new ionization, imaging, machine learning and ion mobility spectrometry tools for probing composition and structure in complex molecular mixtures. In his (limited) free time, Facundo enjoys a number of activities that include camping with his family, rock climbing, paddling, archery, photography and ham radio. 

Vasser Woolley Foundation Chair in Bioanalytical Chemistry
Professor; School of Chemistry and Biochemistry
Phone
404.385.4432
Office
ES&T L1244
Additional Research
Mass Spectrometry (MS) is one of the key analytical methods used to identify and characterize small quantities of biological molecules embedded in complex matrices. Although MS has found widespread use, improvements are still needed to extend its application to the grand challenges of this century. Since starting my position at Georgia Tech in 2004, my group members and I have used an integrated strategy with roots in bioanalytical chemistry, instrumentation development, bioinformatics, and theoretical modeling to focus on questions of great societal and scientific significance. To this purpose, we have integrated with cross-cutting teams devoted to problems that range from explaining the origins of life on Earth and diagnosing cancer at an early stage, to tracking the sources and prevalence of counterfeit pharmaceuticals worldwide. The common theme along these questions is the need for highly accurate tools for quantifying, identifying, and imaging trace chemicals in complex mixtures. Research in our lab uses state-of-the-art mass spectrometry, ion mobility gas-phase separations,ultrahigh performance liquid chromatography, and new soft ion generation techniques. We investigate the obtained data using machine learning and other powerful bioinformatic approaches. Our group is very dynamic, and each student pursues more than one project at a time, usually in collaboration with other group members or with other research groups at GT or elsewhere. Graduate and undergraduate students are trained in a variety of bioanalytical instrumentation/methodologies, with an emphasis on the fundamentals. We are analytical mass spectrometrists at heart, and strive to answer "big" scientific questions or questions with a large societal impact.
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Chemistry & Biochemistry

Andrei Fedorov

Andrei Fedorov
AGF@gatech.edu

Fedorov's background is in thermal/fluid sciences, chemical reaction engineering as well as in applied mathematics. His laboratory works at the intersection between mechanical and chemical engineering and solid state physics and analytical chemistry with the focus on portable/ distributed power generation with synergetic CO2 capture; thermal management of high power dissipation devices and electronics cooling; special surfaces and nanostructured interfaces for catalysis, heat and moisture management; and development of novel bioanalytical instrumentation and chemical sensors. Fedorov joined Georgia Tech in 2000 as an assistant professor after finishing his postdoctoral work at Purdue University.

Professor and Rae S. and Frank H. Neely Chair, Woodruff School Mechanical Engineering
Associate Chair for Graduate Studies, School Mechanical Engineering
Director, Fedorov Lab
Phone
404.385.1356
Office
Love 307
Additional Research

Heat Transfer; power generation; CO2 Capture; Catalysis; fuel cells; "Fedorov's research is at the interface of basic sciences and engineering. His research portfolio is diverse, covering the areas of portable/ distributed power generation with synergetic carbon dioxide management, including hydrogen/CO2 separation/capture and energy storage, novel approaches to nanomanufacturing (see Figure), microdevices (MEMS) and instrumentation for biomedical research, and thermal management of high performance electronics. Fedorov's research includes experimental and theoretical components, as he seeks to develop innovative design solutions for the engineering systems whose optimal operation and enhanced functionality require fundamental understanding of thermal/fluid sciences. Applications of Fedorov's research range from fuel reformation and hydrogen generation for fuel cells to cooling of computer chips, from lab-on-a-chip microarrays for high throughput biomedical analysis to mechanosensing and biochemical imaging of biological membranes on nanoscale. The graduate and undergraduate students working with Fedorov's lab have a unique opportunity to develop skills in a number of disciplines in addition to traditional thermal/fluid sciences because of the highly interdisciplinary nature of their thesis research. Most students take courses and perform experimental and theoretical research in chemical engineering and applied physics. Acquired knowledge and skills are essential to starting and developing a successful career in academia as well as in many industries ranging from automotive, petrochemical and manufacturing to electronics to bioanalytical instrumentation and MEMS."

IRI and Role
Bioengineering and Bioscience > Faculty
Energy > Hydrogen Group
Energy > Research Community
Bioengineering and Bioscience
Energy
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Yuhong Fan

Yuhong Fan
yuhong.fan@biology.gatech.edu
Associate Professor
Georgia Research Alliance Distinguished Scholar
Phone
404-385-1312
Office
Petit Biotechnology Building, Office 2313
Additional Research
Epigenetics, Epigenomics, Chromatin, Gene Expression, Stem Cell Biology, Epidrugs, Mouse Genetics, Cancer, Function of Linker Histones in Mammalian Development, and Stem Cell Differentiation
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Christoph Fahrni

Christoph Fahrni
fahrni@chemistry.gatech.edu

Christoph Fahrni earned a master’s degree in chemistry from the Federal Institute of Technology (ETH, Switzerland) and a Ph.D. degree in chemistry from the University of Basel (Switzerland). After working as a postdoctoral fellow at Northwestern University (Evanston, IL), he joined the School of Chemistry and Biochemistry at the Georgia Institute of Technology in 1999.

Professor
Associate Chair for Graduate and Postdoctoral Programs
Phone
404-385-1164
Office
Petit Biotechnology Building, Office 3310
Additional Research
Metals In Biological Systems. Approximately one third of all known proteins contain metal ions as cofactors and serve a wide variety of functions, such as structure stabilization, catalysis, electron transfer reactions or complex tasks, including signal transduction and gene regulation. Numerous diseases such as haemochromatosis or Menkes disease were found to be related with a defect in metal metabolism. Research is concerned with development of metal specific fluorescent probes for the investigation of the intracellular chemistry of trace elements, the mechanistic study of metalloprotein catalyzed reactions with unusual coordination geometries as well as the development of protein-based, semisynthetic organometallic catalysts in aqueous solution. Fluorescence Probes and Chelators for the Investigation of Intracellular Storage, Trafficking, and Homeostasis of Trace Elements. Until recently, little was known about how eukaryotic cells take up metal ions or regulate intracellular concentrations. Fluorescent chemosensors have been proven to be powerful and nondestructive tools for the study of intracellular metal ion distributions and have provided a wealth of information, including control of muscle contraction, nerve cell communication, hormone secretion, and immune cell activation. Research is concerned with the development of highly specific fluorescent probes for the detailed mechanistic investigation of copper storage and trafficking. Distribution and changes of intracellular copper concentration can be followed in vivo using fluorescence microscopy. Various combinatorial fluorophore libraries are being synthesized, which subsequently are screened for copper binding selectivity. Bioorganometallic Catalysis with Peptide and Protein Ligands. The distribution of metal ions in sea water can be directly correlated with their abundance in biological systems. Consequently, the platinum metals palladium, rhodium, iridium and platinum are not found in any of the natural occurring metalloproteins. Nevertheless, these cations are excellent catalysts for a wide variety of organometallic reactions. Research is focused on combining the rich chemistry of platinum metals with the advantage of proteins to catalyze reactions with high regio- and stereo-selectivity. Novel bioorganometallic catalysts are being developed via redesign of structurally well characterized proteins.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Chemistry & Biochemistry

Alan Emanuel

Alan Emanuel
alan.emanuel@emory.edu

The Emanuel lab investigates how the sense of touch is generated in the mammalian brain by combining modern neurophysiology with mouse genetic manipulations. Dr. Emanuel joined Emory University School of Medicine in January 2023 as an Assistant Professor in the Department of Cell Biology. Before joining Emory, he completed his postdoc at Harvard Medical School during which he investigated the contributions of mechanoreceptor subtypes to the central representation of touch. Dr. Emanuel earned his Ph.D. from Harvard University by studying the biophysical properties of retinal ganglion cell photoreceptors.

Assistant Professor of Cell Biology
Phone
404-727-1286
Office
615 Michael St., Room 615, Atlanta, GA 30322
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience