Robert Guldberg

Robert Guldberg
robert.guldberg@me.gatech.edu

Robert E. Guldberg is the DeArmond Executive Director of the Phil and Penny Knight Campus for Accelerating Scientific Impact and Vice President of the University of Oregon. Guldberg’s research is focused on musculoskeletal mechanobiology, regenerative medicine, and orthopaedic medical devices. Over his 25+ year academic career, Dr. Guldberg has produced over 280 peer-reviewed publications, served as an advisor and board member for numerous biotechnology companies, and co-founded six start-ups. He was previously executive director of the Parker H. Petit Institute for Bioengineering and Bioscience at Georgia Tech from 2009-2018. In 2018, he was selected from a national search to lead the Knight Campus as its inaugural permanent Executive Director, where he has led the creation of its strategic plan, hired faculty into the campus’ first building opened in 2020, and launched the University of Oregon’s first ever engineering degree program. In 2021, he led the launch of Phase 2 of the Knight Campus development with the announcement of a second $500 million gift from Phil and Penny Knight. At the national level, Dr. Guldberg is past Chair of the Americas Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS-AM). He currently serves on the Executive Leadership Council of the Wu Tsai Human Performance Alliance, a $220 million global initiative to promote wellness and peak performance through scientific discovery and innovation. Dr. Guldberg is an elected fellow of TERMIS, the American Society of Mechanical Engineers (ASME), the American Institute for Medical and Biological Engineering (AIMBE), the Orthopaedic Research Society (ORS), and the National Academy of Inventors (NAI).

Vice President and Robert and Leona DeArmond Executive Director
Adjunct Professor
Phone
541-346-3110
Additional Research
Guldberg's research interests focus on musculoskeletal growth and development, functional regeneration following traumatic injury, and degenerative diseases, including skeletal fragility and osteoarthritis. His research is supported by the NIH, NSF, DoD, and several biotechnology companies and has resulted in over 150 book chapters and publications. Guldberg is a Fellow of the American Institute for Medical and Biological Engineering (AIMBE) and holds several national leadership positions.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
University of Oregon > Phil and Penny Knight Campus for Accelerating Scientific Impact

James Gumbart

James Gumbart
gumbart@physics.gatech.edu

My lab is focused on understanding how proteins and other biological systems function at a molecular level. To probe these systems, we carry out molecular dynamics simulations, modeling biological behavior one atom at a time. The simulations serve as a "computational microscope" that permits glimpses into a cell's inner workings through the application of advanced software and high-powered supercomputers. We are particularly interested in how bacteria utilize unique pathways to synthesize proteins and insert them into both the inner and outer membranes, how they import nutrients across two membranes, and how their cell walls provide shape and mechanical strength.

Associate Professor
Phone
404-385-0797
Office
Howey W202
Additional Research
Computational simulations of complex biophysical phenomena involving proteins and other biomolecules.
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Physics

Martha Grover

Martha Grover
martha.grover@chbe.gatech.edu

Grover’s research activities in process systems engineering focus on understanding macromolecular organization and the emergence of biological function. Discrete atoms and molecules interact to form macromolecules and even larger mesoscale assemblies, ultimately yielding macroscopic structures and properties. A quantitative relationship between the nanoscale discrete interactions and the macroscale properties is required to design, optimize, and control such systems; yet in many applications, predictive models do not exist or are computationally intractable.

The Grover group is dedicated to the development of tractable and practical approaches for the engineering of macroscale behavior via explicit consideration of molecular and atomic scale interactions. We focus on applications involving the kinetics of self-assembly, specifically those in which methods from non-equilibrium statistical mechanics do not provide closed form solutions. General approaches employed include stochastic modeling, model reduction, machine learning, experimental design, robust parameter design, and estimation.

Professor, School of Chemical and Biomolecular Engineering
James Harris Faculty Fellow, School of Chemical and Biomolecular Engineering
Member, NSF/NASA Center for Chemical Evolution
Phone
404.894.2878
Office
ES&T 1228
Additional Research

Colloids; Crystallization; Organic and Inorganic Photonics and Electronics; Polymers; Discrete atoms and molecules interact to form macromolecules and even larger mesoscale assemblies, ultIMaTely yielding macroscopic structures and properties. A quantitative relationship between the nanoscale discrete interactions and the macroscale properties is required to design, optimize, and control such systems; yet in many applications, predictive models do not exist or are computationally intractable. The Grover group is dedicated to the development of tractable and practical approaches for the engineering of macroscale behavior via explicit consideration of molecular and atomic scale interactions. We focus on applications involving the kinetics of self-assembly, specific those in which methods from non-equilibrium statistical mechanics do not provide closed form solutions. General approaches employed include stochastic modeling, model reduction, machine learning, experimental design, robust parameter design, estIMaTion, and optimal control, monitoring and control for nuclear waste processing and polymer organic electronics

IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Energy > Research Community
Data Engineering and Science
Bioengineering and Bioscience
Energy
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > School of Chemical and Biomolecular Engineering

Robert Gross

Robert Gross
rgross@emory.edu

Dr. Gross’s research interests include: restorative approaches (including cell and gene therapy) for Parkinson's disease and other neurodegenerative disorders; physiology of movement disorders (Parkinson's disease, tremor, dystonia); novel surgical techniques for epilepsy (e.g. deep brain stimulation, cell and gene therapy). In particular, he has been elucidating the role of axon guidance molecules in the development and reconstruction of the nigrostriatal pathway, which degenerates in P.D. This approach, which encompasses molecular and cellular engineering in combination with neurotransplantation, may be generally useful in reconstructive approaches for many types of nervous system degeneration and injury. 

In July of 2007, Dr. Gross, along with Steve M. Potter, Ph.D. of the Department of Biomedical Engineering at the Georgia Institute of Technology and Emory University, was the recipient of a prestigious grant from The Epilepsy Research Foundation (ERF) for translational research funding awards supporting innovative epilepsy products. The grant supports the development of a novel electrical stimulation approach that directly controls the activity of the brain to attain a more stable state from which seizures will not arise.

MBNA Bowman Chair & Professor
Director and Co-Founder, ENTICe
Director, Translational Neuro-Engineering Laboratory
Director, Stereotactic, Functional Neurosurgery & Epilespsy Surgery
Phone
404-727-2354
Office
Emory WMRB 6311
Additional Research
Neuromodulation using multielecrode arrays, closed loop control theory, and optogenetics for epilepsy and movement disorders. Computational modeling of epilepsy networks for model-based and non-model based feedback control of optogenetic and electrical neuromodulation. Neurorestoration using gene and cell-therapy based approaches for degenerative and injury conditions. The Translational Neuroengineering Research Lab uses neuromodulation for epilepsy using a combination of the following advanced techniques: 1) Multimicroelectrode electrical stimulation using novel parameters informed by optimization of input/output relationships (both model- and non-model based MIMO) using closed-loop control theory including adaptive learning and machine learning approaches; 2) Optogenetic activation and inhibition using all forms of available channels including step-function opsins. These approaches identify novel brain regions that have more widespread control and targets specific cell types for activation and inhibiton. Closed loop control using multielecrode arrays informs and controls neuromodulation. 3) Hardware independent 'luminopsins': novel gene therapy approaches combining bioluminescent proteins with optogenetic channels for hardware independent, widespread and activity-regulatable neuromodulation. We use a combination of in vitro models, animal models (mouse, rat, non-human primate) and human patients undergoing epilepsy and deep brain stimulation surgery as our experimental models. In addition, the laboratory has developed novel gene therapy vectors for neurorestoration targeting key pivotal proteins regulating axon outgrowth in regenerative situations, including for Parkinson's disease, spinal cord injury and retinal degeneration.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University > Department of Neurosurgery

Steven Goudy

Steven Goudy
steven.goudy@emory.edu

Steven L. Goudy, MD, MBA, professor of otolaryngology, director of pediatric otolaryngology at Emory University School of Medicine, founding director of the ACGME-accredited pediatric otolaryngology fellowship at Emory, and medical director of otolaryngology at Childrens Healthcare of Atlanta, is dedicated to providing top-level surgical care to the children of Georgia. 

His clinical practice focuses on maxillary development, Pierre Robin sequence, vascular malformations, and velopharyngeal insufficiency. Working closely with colleagues at the Centers for Disease Control and Prevention, Georgia Institute of Technology, and other local and state entities, Dr. Goudy and his team have developed novel and innovative solutions for care delivery that have brought value to families and improved treatment for patients. 

Dr. Goudys research is focused on defining the biologic processes that guide facial formation for the development of better approaches to regenerating damaged and deficient facial bone and improving wound healing after surgery or injury. Current research projects include an NIH-funded studies to develop immunological approaches to improving oral cavity wound healing, leveraging the oral microbiome to improve oral wound healing and a project to devise cranial facial bone regeneration techniques for pediatric bone replacement procedures. 

Dr. Goudy is dedicated to international service, particularly in the areas of surgical education and delivering surgical care to children with limited access to healthcare. He has traveled globally and performed mission work for more than 20 years in such countries as Guatemala and the Philippines, providing free surgical care to patients with cleft lip and cleft palate and engaging in medical education activities.

Associate Professor
Director, Division of Pediatric Otolaryngology Children's Healthcare of Atlanta
CEO, BeeClear LLC
Additional Research
Dr. Goudy’s lab focuses on craniofacial bone regeneration and the basic biologic mechanisms that control facial bone and soft tissue regeneration. He currently collaborates with investigators at Georgia Institute of Technology and is supported by the National Institutes of Health (NIH) and Children’s Research Trust.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University

Michael Goodisman

Michael Goodisman
michael.goodisman@biology.gatech.edu

Michael Goodisman is interested in understanding how evolutionary processes affect social systems and how sociality, in turn, affects the course of evolution. His research explores the molecular basis underlying sociality, the nature of selection in social systems, the breeding biology of social animals, the process of self-organization in social groups, and the course of development in social species. His teaching interests are centered on the importance of behavior, genetics, and ethics in biological systems. Goodisman also works to improve and advance undergraduate education.

Professor
Associate Chair for Undergraduate Education
Phone
404-385-6311
Office
Cherry Emerson A124
Additional Research
The evolution of sociality represented one of the major transition points in biological history. I am interested in understanding how evolutionary processes affect social systems and how sociality, in turn, affects the course of evolution. My research focuses on the molecular basis underlying sociality, the nature of selection in social systems, the breeding biology of social animals, the process of self-organization in social groups, and the course of development in social species.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Daniel Goldman

Daniel Goldman
dgoldman3@gatech.edu

My research integrates my work in complex fluids and granular media and the biomechanics of locomotion of organisms and robots to address problems in nonequilibrium systems that involve interaction of matter with complex media. For example, how do organisms like lizards, crabs, and cockroaches cope with locomotion on complex terrestrial substrates (e.g. sand, bark, leaves, and grass). I seek to discover how biological locomotion on challenging terrain results from the nonlinear, many degree of freedom interaction of the musculoskeletal and nervous systems of organisms with materials with complex physical behavior. The study of novel biological and physical interactions with complex media can lead to the discovery of principles that govern the physics of the media. My approach is to integrate laboratory and field studies of organism biomechanics with systematic laboratory studies of physics of the substrates, as well as to create mathematical and physical (robot) models of both organism and substrate. Discovery of the principles of locomotion on such materials will enhance robot agility on such substrates

Dunn Family Professor; School of Physics
Director; Complex Rheology And Biomechanics (CRAB) Lab
Phone
404.894.0993
Office
Howey C202
Additional Research

biomechanics; neuromechanics; granular media; robotics; robophysics

IRI and Role
Bioengineering and Bioscience > Faculty
Robotics > Core Faculty
Robotics
Bioengineering and Bioscience
Matter and Systems > Affiliated Faculty
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Physics
Research Areas
Matter and Systems
  • Computing and Communication Technologies
  • Frontiers in Infrastructure

Rudolph Gleason

Rudolph Gleason
rudy.gleason@me.gatech.edu

Rudolph (Rudy) L. Gleason began at Tech in Fall 2005 as an assistant professor. Prior, he was a postdoctoral fellow at Texas A&M University. He is currently a professor in the School of Mechanical Engineering and the School of Biomedical Engineering in the College of Engineering. Gleason’s research program has two key and distinct research aims. The first research aim is to quantify the link between biomechanics, mechanobiology, and tissue growth and remodeling in diseases of the vasculature and other soft tissues. The second research aim is to translate engineering innovation to combat global health disparities and foster sustainable development in low-resource settings around the world. Gleason serves as a Georgia Tech Institute for People and Technology initiative lead for research activities related to global health equity and wellbeing.

Professor, Mechanical Engineering and Biomedical Engineering
Joint Appointment in the School of Biomedical Engineering
Phone
404-385-7218
Office
TEP 205
Additional Research

Cardiovascular mechanics, soft tissue growth and remodeling, and tissue engineering

IRI and Role
Bioengineering and Bioscience > Faculty
People and Technology > Affiliated Faculty
People and Technology > Leadership
Matter and Systems > Affiliated Faculty
People and Technology
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering
Research Areas
Matter and Systems
  • Human-Centric Technologies

Jennifer Glass

Jennifer Glass
jennifer.glass@eas.gatech.edu

The Glass research group studies the microbes that made Earth habitable, and, more specifically, the microbial mechanisms underpinning cryptic transformations of methane and nitrous oxide in oxygen-free ecosystems. Why focus on the microbial world? The Earth has been constantly inhabited for four billion years. For three-quarters of that time, life was solely microbial. Ancient microbes produced the gases that warmed the planet to clement temperatures when the sun was faint, and that invented the molecular machines that drive biogeochemical cycles. The co-evolution of Earth and life is woven into the fabric of our research group, which examines the interplay between microbes and the greenhouses gases that control planetary temperature. Our research informs the microbial metabolisms that (i) made the early Earth habitable for life, (ii) make the deep subsurface habitable for life, (iii) serve as biosignatures for life on exoplanets, and (iv) play crucial roles in regulating atmospheric fluxes of greenhouse gases on our warming planet.

Associate Professor
Phone
404.894.3942
Additional Research

Anaerobic oxidation of methane, Environmental controls on greenhouse gas cycling, with afocus on methane and nitrous oxide, in terrestrial and marineecosystems Biogeochemical cycles of bioessential trace elements Marine microbiology, with a focus on anaerobic metabolisms Influence of trace metal bioavailability on microbial carbon and nitrogen cycling Integrating omic and geochemical datasets Co-evolution of microbial metabolisms and ocean chemistry over Earthhistory,

IRI and Role
Bioengineering and Bioscience > Faculty
Energy > Research Community
Space > Faculty
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Earth and Atmospheric Sciences

Greg Gibson

Greg Gibson
greg.gibson@biology.gatech.edu

Greg Gibson is Professor of Biology and Director of the Center for Integrative Genomics at Georgia Tech. He received his BSc majoring in Genetics from the University of Sydney (Australia) and PhD in Developmental Genetics from the University of Basel. After transitioning to quantitative genetic research as a Helen Hay Whitney post-doctoral fellow at Stanford University, he initiated a program of genomic research as a David and Lucille Packard Foundation Fellow at the University of Michigan. He joined the faculty at Georgia Tech in Fall of 2009, after ten years at North Carolina State University where he developed tools for quantitative gene expression profiling and genetic dissection of development in the fruitfly Drosophila. He is now collaborating with the Center for Health Discovery and Well Being on integrative genomic analyses of the cohort. Dr Gibson is an elected Fellow of the American Association for the Advancement of Science, and serves as Section Editor for Natural Variation for PLoS Genetics. He has authored a prominent text-book, a "Primer of Genome Science" as well as a popular book about genetics and human health, "It Takes a Genome".

Professor
Director, Center for Integrative Genomics
Adjunct Professor, School of Medicine, Emory University
Phone
404-385-2343
Office
EBB 2115A
Additional Research
Quantitative Evolutionary Genetics. After 15 years working on genomic approaches to complex traits in Drosophila, my group has spent much of the past 10 years focusing on human quantitative genetics. We start with the conviction that genotype-by-environment and genotype-by-genotype interactions are important influences at the individual level (even though they are almost impossible to detect at the population level). We use a combination of simulation studies and integrative genomics approaches to study phenomena such as cryptic genetic variation (context-dependent genetic effects) and canalization (evolved robustness) with the main focus currently on disease susceptibility.​ Immuno-Transcriptomics.As one of the early developers of statistical approaches to analysis of gene expression data, we have a long-term interest in applications of transcriptomics in ecology, evolution, and lately disease progression. Since blood is the mostaccessible human tissue, we've examined how variation is distributed within and among populations, across inflammatory and auto-immune states, and asked how it relates to variation in immune cell types. Our axes-of-variation framework provides a new way of monitoring lymphocyte, neutrophil, monocyte and reticulocyte profiles from whole peripheral blood. Most recently we have also been collaborating on numerous studies of specific tissues or purified cell types in relation to such diseases as malaria, inflammatory bowel disease, juvenile arthritis, lupus, and coronary artery disease. Predictive Health Genomics. Personalized genomic medicine can be divided into two domains: precision medicine and predictive health. We have been particularly interested in the latter, asking how environmental exposures and gene expression, metabolomic and microbial metagenomics profiles can be integrated with genomesequencing or genotyping to generate health risk assessments. A future direction is incorporation of electronic health records into genomic analyses of predictive health. Right now it is easier to predict the weather ten years in advance than loss of well-being, but we presume that preventative medicine is a big part of the future of healthcare.​
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences