Amanda Stockton

Amanda Stockton's profile picture
astockto@gatech.edu

Education
B.S., Chemistry, Massachusetts Institute of Technology, 2004; B.S., Aerospace Engineering, Massachusetts Institute of Technology, 2004; M.A., Chemistry, Brown University, 2006; Ph.D., Chemistry, University of California Berkeley, 2010

Research
Dr. Stockton joined the School of Chemistry and Biochemistry at the Georgia Institute of Technology in January 2015. Her research plans include (1) instrument development for in situ organic analysis in the search for extraterrestrial life, (2) microfluidic approaches to experimentally evaluating hypotheses on the origin of biomolecules and the emergence of life, and (3) terrestrial applications of these technologies for environmental analysis and point-of-care diagnostics.

Associate Professor
Phone
(404) 894-4090
Office
MoSE 1100K
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
Matter and Systems > Affiliated Faculty
Space > Faculty
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Chemistry & Biochemistry
Research Areas
Matter and Systems
  • Frontiers in Infrastructure
Space

Alberto Stolfi

Alberto Stolfi's profile picture
alberto.stolfi@biosci.gatech.edu

We study the simple larval nervous system of our closest invertebrate relatives, the tunicates. Tunicates, like us, belong to the Chordate phylum, but have very simple embryos and compact genomes. The laboratory model tunicate Ciona has only 177 neurons and is the only chordate with a fully mapped "connectome". We take advantage of this simplicity to understand molecular mechanisms that may underlie human neurodevelopment. We use transcriptome profiling to assay global transcriptional dynamics in neural progenitors during Ciona development, and use CRISPR/Cas9 to knock out important transcription factors and their downstream targets to understand how these gene networks control neuronal specification, morphology, physiology, neurotransmitter identity, and connectivity.

Assistant Professor
Phone
404-385-5975
Office
EBB 4014
Additional Research
We seek to answer how animal behavior is set up by the collective behaviors of individual cells, over the entire course of brain and spinal cord development. We want to understand how gene activity can instruct developing neurons to move around, change shape, and connect to other cells. To do this, we study the simple larval nervous system of our closest invertebrate relatives, the tunicates. Tunicates, like us, belong to the Chordate phylum, but have very simple embryos and compact genomes. The laboratory model tunicate Ciona has only 177 neurons and is the only chordate with a fully mapped "connectome". We take advantage of this simplicity to understand molecular mechanisms that may underlie human neurodevelopment.
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Jonathan Stiles

Jonathan Stiles's profile picture
jstiles@msm.edu

Graduate
University of Salford
Degree: Doctor of Philosophy

Undergraduate
University of Ghana
Degree: Bachelor of Science

Research Interests

Molecular pathogenesis of neglected diseases that affect the central nervous system (CNS) with emphasis on cerebral malaria and African trypanosomiasis ("Sleeping Sickness")


Our research is focused on three main areas; a) Understanding pathogen-induced brain encephalopathy, and b) Research and development of anti-parasitic drugs and c) Understanding immunopathogenesis of Sickle Cell Disease
Pathogen-induced brain neuropathy (Cerebral malaria & African Trypanosomiasis). In collaboration with the Neuroscience Institute here at MSM, Queens College, NY, University of Ghana Medical School, and CDC, Atlanta, GA, we are studying the role of cerebral malaria (CM) and African trypanosomiasis (HAT) in brain neuropathy. Both diseases impact the central nervous system and result in diffuse encephalopathy in the infected. The encephalopathy associated with malaria for example is associated with 10-14% of mortality with an estimated annual death of 1-2.5 million annual deaths globally. The molecular mechanisms controlling these outcomes are unclear. Current studies ignore malaria-induced gross neurological defects and the impact of this disease on learning, cognitive function and neuro-psychology. The absence of effective vaccines or drugs to protect against these diseases coupled with the increasing drug resistance has resulted in the re-emergence of malaria and trypanosomiasis in the tropics and subtropics. We are employing bio-informatics, functional genomics, and proteomics in human and mouse disease models to study the role of immunomodulators, apoptosis, and signaling factors in CM and HAT-induced brain pathology.

Research & Development of anti-parasitic drugs. In collaboration with Yale University, University of Mississippi Medical Center, (UMC), and Noguchi Medical Research Institute in Ghana, we are targeting cation homeostasis mechanisms of trypanosomes during infection. Millions of Latin Americans infected with Trypanosoma cruzi (Chagas disease) suffer chronic splenomegaly, cardiac myopathy and megacolonitis while millions are at risk of infection with African trypanosomes (HAT) in Africa. HIV infection exacerbates susceptibility to and further complicates malaria and HAT. Available drugs are very toxic while supplies are precariously low. We are targeting cation pumps (cation ATPases) utilized by trypanosomes for uptake of nutrients, as well as for regulating cell volume and intracellular pH as drug targets. Blocking these ion pumps by specific drugs or antibodies inhibit proliferation of these parasites in vitro and in their hosts. By understanding parasite ion homeostasis during infection, we hope that novel strategies to intervene by drugs may be developed.

Genomics & Immunopathogenesis of Sickle Cell Disease SCD. In collaboration with Drs. Adamkiewicz, Hibbert, Gee, and Buchanan at Morehouse School of Medicine, we provide postdoctoral research training in various aspects of sickle cell disease (SCD) immuno-pathogenesis in human and murine models. SCD and other hemoglobinopathies are responsible for significant morbidity and mortality among people of African, Mediterranean and South Asian descent.

Professor, Microbiology, Biochemistry & Immunology
Phone
(404) 752-1585
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Morehouse College

Steve Stice

Steve Stice's profile picture
sstice@uga.edu

Steve Stice is Co-Founder and Chief Scientific Officer of ArunA Biomedical, Inc, where he directs the company’s clinical and research operations. He is also University of Georgia, DW Brooks Distinguished Professor and Director of the Regenerative Bioscience Center, and holds a Georgia Research Alliance Eminent Scholar endowed chair. 

Prior to joining ArunA, Stice was the co-founder and served as both Chief Scientific Officer and Chief Executive Officer of Advanced Cell Technology, the first U.S. company to advance to human clinical trials using human pluripotent stem cells. He also co-founded startups Prolinia and Cytogenesis, the latter of which has since merged with ViaCyte. 

Stice was recruited to the University of Georgia by the Georgia Research Alliance (GRA) and holds an endowed chair as a GRA Eminant Scholar. Additionally, Stice serves as the Director of the Univeristy of Georgia’s Regenerative Bioscience Center, co-directs The Regenerative Engineering and Medicine Research Center (REM), a joint collaboration between Emory University, Georgia Institute of Technology and UGA, is a group leader of Emergent Behaviors of Integrated Cellular Systems, a National Science Foundation Center founded by the Massachusetts Institute of Technology. Stice also sits on the toxicology Scientific Advisory Board for the Food and Drug Administration (FDA). 

Stice received a Masters of Science in Reproductive Biology from Iowa State University and a Doctor of Philosophy, Developmental Biology and Embryology, from the University of Massachusetts.

D.W. Brooks Distinguished Professor
Co-Director, Regenerative Engineering and Medical Center (REM)
Director, UGA Regenerative Bioscience Center
Georgia Research Alliance Eminent Scholar
Phone
706-583-0071
Additional Research
Finding new treatments for degenerative diseases such Parkinson's, Alzheimer's and Multiple Sclerosis andneural injuries spinal cord and head trauma as well as treating cardiovascular diseases (heart and blood vessel repair) through stem cell technologies. Animal stem cells and cloning animal agriculture, veterinary and biomedicine applications.
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
University of Georgia > Department of Animal and Dairy Science

Frank Stewart

Frank Stewart's profile picture
frank.stewart@biology.gatech.edu

I am an environmental microbiologist interested in the dynamics of microbial systems.  My research is motivated by the beliefs that microbes are a frontier for natural history and scientific discovery, and that exploring this frontier is necessary and important for understanding biological diversity and its changing role in ecosystem processes. The first major research theme in my lab explores how aquatic microbes respond to environmental change, notably declines in ocean oxygen content.  The second major theme explores how life in symbiosis drives microbial evolution and ecology.  My research targets diverse systems, from the marine water column to the intestinal microbiomes of fishes.  This research aims to identify metabolic properties that underlie the ecology of microbes and microbe-host systems, the evolutionary context under which these functions arose, and the role of these functions in ecosystem-scale processes in a changing environment.  

I am an Associate Professor in the Department of Microbiology and Immunology at Montana State University and an Adjunct Professor in the School of Biological Sciences at Georgia Tech.  I received a B.A. in Biology from Middlebury College and a Ph.D. in Organismic and Evolutionary Biology from Harvard University.  I worked as a Postdoctoral Fellow at MIT for two years before moving to Georgia Tech in January 2011.  In February 2020, I moved my lab to the mountains of Montana.  My work has been recognized through an NSF CAREER award, a Sloan Research Fellowship, and a Simons Foundation Early Career investigator award.  

Adjunct Associate Professor
Phone
404-894-5819
Office
ES&T 1242
Additional Research
Bacteria and Archaea constitute the overwhelming majority of genetic and metabolic diversity on this planet. To understand these organisms in their native habitats, environmental microbiologists are tasked with two fundamental questions. First, how do ecological and evolutionary processes (e.g., symbiosis, competition, recombination, natural selection) create and structure genetic diversity? Second, how is this genetic diversity linked to the diverse biogeochemical functions of microorganisms in nature? Our research explores these questions for marine microorganisms, using the tools of genomics and molecular biology. We are particularly interested in how microbial genome evolution and physiology are affected by symbiotic interactions with higher taxa. In tandem with this work, we study free-living microorganisms, as they provide important reference points for understanding symbiont biology and mediate key global biogeochemical cycles in the ocean's water column and sediments. In particular, we are interested in how oxygen loss affects the diversity and metabolism of marine microbes. Our research integrates the broad fields of microbiology, molecular evolution, and marine biology. This work has both descriptive and experimental components, and involves a blend of field, molecular, and bioinformatic techniques, the latter focused in part on the analysis of high-throughput sequencing datasets. We welcome inquiries from potential students, post-docs, and collaborators who share these interests.
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Garrett Stanley

Garrett Stanley's profile picture
garrett.stanley@bme.gatech.edu

Garrett Stanley is the McCamish Foundation Distinguished Chair in the Department of Biomedical Engineering at Georgia Tech and Emory University and is the Co-Director of the Georgia Tech Neural Engineering Center. He has formal training, both at undergraduate and doctorate levels, in engineering (specifically trained in Control Theory through all of his graduate work), and has worked extensively in the field of neuroscience, specifically in sensory processing in the brain, and more specifically in vision and somatosensation (touch). 

From 1999 to 2007, he was an Associate Professor in the Division of Engineering & Applied Sciences at Harvard University, where he was the leader of the Harvard Biocontrols Laboratory. Professor Stanley is now a faculty member in the Department of Biomedical Engineering at Georgia Tech/Emory University (2008-2013 Associate Professor, 2014-present Full Professor), and leads several programmatic efforts at the interface between basic neuroscience and neurotechnology (Co-Direct the GT Neural Engineering Center, Direct Computational Neuroscience training program, Director of Graduate Studies, etc.). In terms of research, he is the leader of the Neural Coding group in the Laboratory for Neuroengineering. 

The research of his group has been funded by the National Institute of Health, National Science Foundation, the Office of Naval Research, DARPA, and several private foundations. Prof. Stanley’s group routinely publishes our research in the top Neuroscience journals, along with more technical work in engineering journals. He is considered a leader in the field nationally and internationally.

McCamish Foundation Distinguished Chair
Carol Ann and David D. Flanagan Professor
BME Faculty Fellow
Phone
404-385-5037
Office
UAW 3107
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
Data Engineering and Science > Faculty
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering

Simon Sponberg

Simon Sponberg's profile picture
simon.sponberg@physics.gatech.edu

During his graduate work at UC, Berkeley, Simon sought to uncover general principles of animal locomotion that reveal control strategies underlying the remarkable stability and maneuverability of movement in nature. His work has demonstrated the importance animals’ natural dynamics for maintaining stability in the absence of neural feedback. His research emphasizes the importance of placing neural control in the appropriate dynamical context using mathematical and physical models. He has collaborated with researchers at four other institutions to transfer these principles to the design of the next generation of bio-inspired legged robots. 

Simon received his Ph.D. in Integrative Biology at UC, Berkeley and has been a Hertz Fellow since 2002. His work has led to fellowships and awards from the National Science Foundation, the University of California, the Woods Hole Marine Biological Institute, the American Physical Society, the Society of Integrative and Comparative Biology, and the International Association of Physics Students. He is also currently affiliated the new Center for Interdisciplinary Bio-Inspiration in Education and Research (CIBER) at Berkeley.

Dunn Family Associate Professor; Physics & Biological Sciences
Director; Agile Systems Lab
Phone
404.385.4053
Office
Howey C205
Additional Research
A central challenge for many organisms is the generation of stable, versatile locomotion through irregular, complex environments. Animals have evolved to negotiate almost every environment on this planet. To do this, animals'nervous systems acquire, process and act upon information. Yet their brains must operate through the mechanics of the body's sensors and actuators to both perceive and act upon the environment. Ourresearch investigates howphysics and physiologyenable locomoting animals to achieve the remarkable stability and maneuverability we see in biological systems. Conceptually, this demands combining neuroscience, muscle physiology, and biomechanics with an eye towards revealing mechanism and principle -- an integrative science of biological movement. This emerging field, termedneuromechanics, does for biology what mechatronics, the integration of electrical and mechanical system design, has done for engineering. Namely, it provides a mechanistic context for the electrical (neuro-) and physical (mechanical) determinants of movement in organisms. Weexplore how animals fly and run stably even in the face of repeated perturbations, how the multifuncationality of muscles arises from their physiological properties, and how the tiny brains of insects organize and execute movement.
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Robotics > Core Faculty
Robotics
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Physics

Stephen Sprigle

Stephen Sprigle's profile picture
stephen.sprigle@design.gatech.edu

Stephen Sprigle is a Professor at the Georgia Institute of Technology with appointments in Bioengineering, Industrial Design and the George W. Woodruff School of Mechanical Engineering. 

A biomedical engineer with a license in physical therapy, Sprigle directs the Rehabilitation Engineering and Applied Research Lab (REARLab), which focuses on applied disability research and development. The REARLab’s research interests include the biomechanics of wheelchair seating and posture, pressure ulcer prevention, and manual wheelchair propulsion. Its development activities include standardized wheelchair and cushion testing and the design of assistive and diagnostic technologies. Sprigle teaches design-related classes in both the Schools of Industrial Design and Mechanical Engineering.

Professor
Phone
404-385-4302
Office
Architecture 0155
Additional Research
Applied research and device development targeting the increased heath and function of persons with disabilities. Specific areas of interest include: wheeled mobility and seating, pressure ulcer prevention and treatment; design of diagnostic tissue interrogation devices; design of assistive technology. Wheeled Mobility and Seating; Pressure Ulcer Prevention and Treatment; Design of Diagnostic Tissue Interrogation Devices; Design of Assistive Technologies
IRI/Group and Role
Bioengineering and Bioscience > Faculty
People and Technology > Affiliated Faculty
People and Technology
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering
Georgia Institute of Technology > College of Design > School of Industrial Design

Sharon Sonenblum

Sharon Sonenblum's profile picture
sharon.sonenblum@coa.gatech.edu

Educational Experience:
Doctor of Philosophy, December 2009, Georgia Institute of Technology (Bioengineering), Masters of Science, May 2003, Brown University (Bioengineering), Bachelor of Science, May 2002, Brown University (Mechanical Engineering)
Research Interests:
Wheeled mobility and seating, Pressure ulcer prevention and early detection, Assistive technology, Rehabilitation engineering.

Senior Research Scientist
Phone
404-385-0633
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Terry Snell

Terry Snell's profile picture
terry.snell@biosci.gatech.edu

Terry Snell, an Emeritus Professor in the School of Biological Sciences, is a member of the Parker H. Petit Institute for Bioengineering and Bioscience.

Professor Emeritus
Phone
404-385-4498
Office
Cherry Emerson 201
Additional Research
Chemical ecology of zooplankton; mate recognition; evolutionary ecology; aquatic toxicology; gene expression in response to environmental stress; aquaculture. 
IRI/Group and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences
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