As a physician scientist, Dr. Bauser-Heaton's clinical and research interests are focused on pulmonary vascular disease. Our 3D bioprinted disease modeling allows study of patient specific geometries and cell types for potential therapeutic targets. Through collaborations with several IBB members, we have created a pipeline for disease modeling that includes computational fluid dynamics, particle image velocity measurement of shear stress, additive manufacturing and iPSC utilization. 

Gary J. Bassell, Ph.D. joined the faculty at Emory University School of Medicine in 2005, where he is currently Professor and Chair of the Department of Cell Biology. His personal lab’s main interest is in understanding the mechanisms and functions of mRNA transport and local protein synthesis in neurons of the central and peripheral nervous system. The lab utilizes in vitro and in vivo mouse models and induced pluripotent stem cells (iPSCs) to study the basic mechanism, regulation and function of mRNA localization and local translation in axonal growth cones and dendritic spines. Prior to moving Emory, Dr. Bassell was a member of the faculty at the Albert Einstein College of Medicine, in the Department of Anatomy and Structural Biology (1995-1998) and subsequently in the Department of Neuroscience and Rose Kennedy Center for Mental Retardation (1998-2005). 

Ryanodine receptors (RyRs) are intracellular ion channels that mediate the release of calcium from intracellular stores. RyR1 and RyR2 are the predominate isoforms in skeletal and cardiac muscle, respectively where they play a central role in excitation-contraction coupling. RyRs are the largest known ion channels and are regulated by a multitude of endogenous effectors including ions, small molecules, and accessory proteins. An area of interest is the regulation of these channels by endogenous effectors, especially as it relates to altered contractile function associated with cardiac ischemia, skeletal muscle fatigue and aging. 

Because of their central role in cellular calcium regulation, defects in RyR channels can lead to potentially fatal disorders. Mutations in RyR1 give rise to the pharmacogenetic skeletal muscle disorder, malignant hyperthermia (MH). RyR2 mutations have been identified in catecholaminergic polymorphic ventricular tachycardia. We are interested in determining the molecular mechanisms by which these mutations alter RyR channel function. 

We analyze channel function on multiples levels of organization. Sarcoplasmic reticulum vesicle [3H]ryanodine binding is used to examine large populations of channels. We incorporate channels into artificial lipid bilayers in order to record single channel currents and assess channel kinetics. Calcium release from permeabilized muscle fibers provides a method of examining RyR function in situ. My research has two long-range goals. The first is to understand how intracellular calcium is regulated and how alterations in the regulation effects cell function. The second goal is to understand the RyR regulatory sites that might be exploited for the development of pharmacological compounds to treat disorders of cellular calcium regulation.

Stephen Balakirsky is the Chief Scientist for the Aerospace, Transportation & Advanced Systems Laboratory at the Georgia Tech Research Institute (GTRI), and the Director of Technical Initiatives at the Petit Institute for Bioengineering and Bioscience (IBB) at Georgia Tech.

Balakirsky’s research interests include robotic architectures, planning, bio-automation, robotic standards, and autonomous systems testing. His work in knowledge driven robotics couples real-time sensors and knowledge repositories to allow for flexibility and agility in robotic systems ranging from assembly and manufacturing systems to surveillance and logistics systems. The framework promotes software reuse and the ability to detect and correct for execution errors.

Previously, Balakirsky worked as a project manager at the National Institute of Standards and Technology (NIST) and was a senior research engineer at the Army Research Laboratory (ARL). At ARL, Balakirsky performed mobile robotics research in several areas, including command and control, mapping, human-computer interfaces, target tracking, vision processing and tele-operated control.

Julia Babensee is an Associate Professor in the Walter H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. Dr. Babensee is affiliated with the Petit Institute for Bioengineering and Bioscience and the Georgia Tech/Emory Center for the Engineering of Living Tissue. 

Dr. Babensee is a member of the Cell and Molecular Biology Research Program at Winship Cancer Institute. She is also a permanent member of the NIH Bioengineering, Technology and Surgical Sciences study section. She is actively involved in several professional societies with service including SFB Member-at-Large (2008-2009) and Program Chair for the 2012 Annual Meeting of the Biomedical Engineering Society in Atlanta, Georgia. 

Her research program is in the area of engineering of inflammatory and immune responses focused on understanding host responses to combination products. Her research interests also include: Biomaterial interactions with dendritic cells, tissue engineering for rheumatoid arthritis, and biomaterial-applied immunology.

Babensee received her Ph.D. from University of Toronto in Toronto, Canada. She completed her postdoctoral fellowship at Rice University and Baylor College of Medicine.

Turgay Ayer is the Virginia C. and Joseph C. Mello Chair and a professor in the H. Milton Stewart School of Industrial and Systems Engineering at Georgia Tech. Ayer also serves as the research director for healthcare analytics and business intelligence in the Center for Health & Humanitarian Systems at Georgia Tech and holds a courtesy appointment at Emory Medical School.

His research focuses on healthcare analytics and socially responsible business analytics with a particular emphasis on practice-focused research. His research papers have been published in top tier management, engineering, and medical journals, and covered by popular media outlets, including the Wall Street Journal, Washington Post, U.S. News, and NPR.

Ayer has received over $2.5 million grant funding and several awards for his work, including an NSF CAREER Award (2015), first place in MSOM Responsible Research in Operations Management (2019), first place in the MSOM Best Practice-Based Research Competition (2017), INFORMS Franz Edelman Laureate Award (2017), and Society for Medical Decision Making Lee Lusted Award (2009).

Ayer serves an associate editor for Operations Research, Management Science, and MSOM, and is a past president of the INFORMS Health Application Society. He received a B.S. in industrial engineering from Sabanci University in Istanbul, Turkey, and his M.S. and Ph.D. degrees in industrial and systems engineering from the University of Wisconsin–Madison.

As a student, Aqua Asberry, HT(ASCP)CM, studied chemistry and was determined to become a forensic scientist. An intuitive mentor steered her towards histology, and Ms. Asberry is currently Research Histology Manager at Parker H. Petit Institute for Bioengineering and Bioscience at Georgia Tech.