Michelle Gaines, Ph.D.

Michelle Gaines, Ph.D.
mgaines6@spelman.edu

Michelle’s research is themed around designing and characterizing the surface chemical properties of synthetic and natural polymer systems. They will be used to develop multifunctional biomaterial substrates for regenerative medicine, cancer treatment, and personal care products. The goals of the Gaines Lab are achieved by marrying Polymer Synthesis, Materials Science, Cell Biology & Spectroscopy.

Assistant Professor
Phone
404.270.5743
Office
350 Spelman Lane, S.W.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience

Jessica Forness

Jessica Forness
jgilmore3@gatech.edu
Center Manager of the Center for the Study of Systems Biology
Phone
404-407-8976
Office
EBB 2153
IRI and Role
Bioengineering and Bioscience > Research Professional
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology

Stefan France

Stefan France
stefan.france@chemistry.gatech.edu

Stefan France is an Associate Professor in the School of Chemistry and Biochemistry. Professor France earned his B.S. in Chemistry (2000) from Duke University and a M.A. (2003) and Ph.D. (2005) in Organic Chemistry from Johns Hopkins University. His research group focuses on experimental methodology development, natural product synthesis, and medicinal chemistry. Owing to Prof. France's avid interest in undergraduate research, his research group has mentored and trained more than 60 undergraduates (both Georgia Tech and non-Georgia Tech students). Professor France has been the recipient of several awards for his research, mentorship, and teaching including: the 2018 Georgia Tech-Georgia Power Professor of Excellence; the 2015 Georgia Tech Senior Faculty Outstanding Undergraduate Mentor Award; the 2014 Georgia Tech Faculty Award for Academic Outreach; the 2014 Georgia Tech Hesberg Teaching Award; the 2013 Georgia Tech Sigma Xi Young Faculty Award; the 2012 National Organization for the Professional Advancement for Black Chemists and Chemical Engineers (NOBCChE) Lloyd N. Ferguson Young Scientist Award; and the 2011 National Science Foundation (NSF) CAREER Award. He heads the Chemistry FAST Program, a NSF Research Experiences for Undergraduates (REU) Site, and also serves as Chair of the NSF Chemistry REU Leadership Group.

Associate Professor
Phone
404-385-1796
Office
MoSE 2100K
Additional Research
Our group is interested in the design of efficient methodologies to accomplish the formation of carbon-carbon and carbon-heteroatom bonds with the intent to apply the methodology toward the synthesis of complex natural and unnatural targets. Natural Product Synthesis. Approaches to natural products not only inspire the development of new synthetic strategies, but often unveil unexpected and often interesting reactivity. Targets are chosen for their interesting biological activity along with their sheer complexity. We are interested in exploring both modular and convergent approaches to complex targets that enable facile derivatization for the development of combinatorial libraries. Medicinal Chemistry. Medicinal or pharmaceutical chemistry lies at the intersection of chemistry and pharmacy. Our group is interested in the design, synthesis and development of pharmaceutical drugs, or other chemical entities suitable for therapeutic use. We are further interested in the study of their biological properties and their quantitative structure-activity relationships (QSAR). Given that medicinal chemistry is a highly interdisciplinary science, we aim to establish several collaborations with biologists, biochemists, and computational chemists to facilitate the design and development process. In particular, we aim to develop therapeutics toward the treatment of various forms of cancer, HIV, diabetes, and neurological disorders, such as Alzheimer's and Parkinson's disease.
IRI and Role
Bioengineering and Bioscience > Faculty
Renewable Bioproducts > Faculty
Bioengineering and Bioscience
Renewable Bioproducts
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Chemistry & Biochemistry

Ming-fai Fong

Ming-fai Fong
ming-fai.fong@bme.gatech.edu

Ming-fai Fong is an Assistant Professor in the Coulter Department of Biomedical Engineering at Georgia Tech and Emory. She received her BS in Mechanical Engineering from MIT and Ph.D. in Neuroscience from Emory University. She completed her postdoctoral training in the Department of Brain and Cognitive Sciences at MIT and a visiting lectureship in the Neuroscience Department at Wellesley College.
 

Assistant Professor
Phone
404.894.6059
Office
UAW 3103
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience

Craig Forest

Craig Forest
cforest@gatech.edu

Craig Forest is a Professor and Woodruff Faculty Fellow in the George W. Woodruff School of Mechanical Engineering at Georgia Tech where he also holds program faculty positions in Bioengineering and Biomedical Engineering. He conducts research on miniaturized, high-throughput robotic instrumentation to advance neuroscience and genetic science, working at the intersection of bioMEMS, precision machine design, optics, and microfabrication. Prior to Georgia Tech, he was a research fellow in Genetics at Harvard Medical School. He obtained a Ph.D. in Mechanical Engineering from MIT in June 2007, M.S. in Mechanical Engineering from MIT in 2003, and B.S. in Mechanical Engineering from Georgia Tech in 2001. He is cofounder/organizer of one of the largest undergraduate invention competitions in the US—The InVenture Prize, and founder/organizer of one of the largest student-run makerspaces in the US—The Invention Studio. He was a recently a Fellow in residence at the Allen Insitutte for Brain Science in Seattle WA; he was awarded the Georgia Tech Institute for BioEngineering and BioSciences Junior Faculty Award (2010) and was named Engineer of the Year in Education for the state of Georgia (2013). He is one of the inaugural recipients of the NIH BRAIN Initiative Grants, a national effort to invent the next generation of neuroscience and neuroengineering tools. In 2007, he was a finalist on the ABC reality TV show "American Inventor.”

Professor
Phone
404.385.7645
Office
Petit Biotechnology Building, Office 1310
Additional Research
The Precision Biosystems Laboratory is focused on the creation and application of miniaturized, high-throughput, biological instrumentation to advance genetic science. The development of instruments that can nimbly load, manipulate, and measure many biological samples - not only simultaneously, but also more sensitively, more accurately, and more repeatably than under current approaches - opens the door to essential, comprehensive biological system studies. Our group strives to develop these tools, validate their performance with meaningful biological assays, and with our collaborators, pursue discoveries using the instruments. These instruments, and the discoveries they enable, could open new frontiers forthe design and control of biological systems.
IRI and Role
Bioengineering and Bioscience > Faculty
Manufacturing > Affiliated Faculty
Manufacturing
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Candace Fleischer

Candace Fleischer
ccfleis@emory.edu

Candace C. Fleischer, PhD, is an Assistant Professor in the Department of Radiology and Imaging Sciences at the Emory University School of Medicine. Dr. Fleischer also holds a faculty appointment at the Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University. She serves as the director of the Biomedical Spectroscopy and Imaging Laboratory.

Dr. Fleischer is a spectroscopist with formal training in physical chemistry and biomedical engineering. Her research group is highly collaborative and focused on the development of new MR spectroscopy and imaging technologies for biomedical and translational applications. 

Current projects include the development of magnetic resonance-based methods for identifying inflammatory biomarkers in malignant brain tumors; and creating new tools for non-invasively measuring brain temperature with applications in cerebrovascular and cardiovascular injury. Her laboratory is also committed to community outreach and increasing scientific literacy.

Assistant Professor of Radiology and Imaging Sciences, Emory University
Assistant Professor of Biomedical Engineering, Georgia Tech and Emory University
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University > Department of Radiology and Imaging Sciences

M.G. Finn

mgfinn@gatech.edu
Professor, James A. Carlos Family Chair for Pediatric Technology
Phone
404-385-0906
Office
MoSE 2201B
Additional Research

We develop chemical and biological tools for research in a wide range of fields. Some of them are briefly described below; please see our group web page for more details. Chemistry, biology, immunology, and evolution with viruses. The sizes and properties of virus particles put them at the interface between the worlds of chemistry and biology. We use techniques from both fields to tailor these particles for applications to cell targeting, diagnostics, vaccine development, catalysis, and materials self-assembly. This work involves combinations of small-molecule and polymer synthesis, bioconjugation, molecular biology, protein design, protein evolution, bioanalytical chemistry, enzymology, physiology, and immunology. It is an exciting training ground for modern molecular scientists and engineers. Development of reactions for organic synthesis, chemical biology, and materials science. Molecular function is what matters most to our scientific lives, and good chemical reactions provide the means to achieve such function. We continue our efforts to develop and optimize reactions that meet the click chemistry standard for power and generality. Our current focus is on highly reliable reversible reactions, which open up new possibilities for polymer synthesis and modification, as well as for the controlled delivery of therapeutic and diagnostic agents to biological targets. Traditional and combinatorial synthesis of biologically active compounds.We have a longstanding interest in the development of biologically active small molecules. We work closely with industrial and academic collaborators on such targets as antiviral agents, compounds to combat tobacco addiction, and treatments for inflammatory disease.

IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Affiliated Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Chemistry & Biochemistry

Alberto Fernandez-Nieves

Alberto Fernandez-Nieves
afn3@gatech.edu

Soft materials are materials whose properties are determined by internal structures with dimensions between atomic sizes and macroscopic scales. They are characterized by energies that are typically comparable to kT. As a result, they have low elastic moduli, often ~1-10 Pascals. Typical soft materials include liquid crystals, polymers, colloidal suspensions and emulsion drops. These materials, unlike conventional simple liquids, are locally heterogeneous and can have broken symmetries that affect their physical properties. Hence, although they often exhibit liquid-like behavior, soft materials also often exhibit properties of solids. Our laboratory studies the physics of soft materials with a focus on the connection between microscopic order and macroscopic properties. The underlying theme is to pursue basic understanding and address fundamental questions. However, we also address applied problems and pursue industrial collaborations since many of the materials we study can be viewed as model systems for those that are often used in applications. Current projects include (i) studying the phase and non-equilibrium behavior and properties of dense microgel suspensions, (ii) understanding the consequences of confinement and curvature over the equilibrium states of ordered materials, which in many cases require the existence of topological defects in their ground states, and (iii) electrohydrodynamics of toroidal droplets and jets.

Associate Professor, School of Physics
Director, Soft Condensed Matter Laboratory
Phone
404.385.3667
Office
Boggs B19
Additional Research

Physics of soft materials with a focus on the connection between microscopic order and macroscopic properties, hydrodynamics, advanced characterization, polymers, computational mechanics

IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences

Facundo Fernandez

Facundo Fernandez
facundo.fernandez@chemistry.gatech.edu

Facundo was born in Buenos Aires, Argentina. He received his MSc in Chemistry from the College of Exact and Natural Sciences, Buenos Aires University in 1995 and his PhD in Analytical Chemistry from the same University, in 1999.  In August 2000, he joined the research group of Prof. Richard N. Zare in the Department of Chemistry at Stanford University.  His work focused on several aspects of Hadamard transform time-of-flight mass spectrometry with an emphasis on coupling this technique to capillary-format separation methods.  In 2002, he joined the group of Prof. Vicki Wysocki in the Department of Chemistry at the University of Arizona, to develop novel tandem mass spectrometers for gas-phase peptide ion studies. In 2004 he joined the School of Chemistry and Biochemistry at the Georgia Institute of Technology where he currently holds the position of Vasser-Woolley Endowed Professor in Bioanalytical Chemistry and Associate Chair for Research and Graduate Training. He is the author of over 185 peer-reviewed publications and numerous invited presentations at national and international conferences. He has received several awards, including the NSF CAREER award, the CETL/BP Teaching award, the Ron A. Hites best paper award from the American Society for Mass Spectrometry, and the Beynon award from Rapid Communications in Mass Spectrometry, among others. He serves on the editorial board of The Analyst and as an Associate editor for the Journal of the American Society for Mass Spectrometry. His current research interests include the field of metabolomics and the development of new ionization, imaging, machine learning and ion mobility spectrometry tools for probing composition and structure in complex molecular mixtures. In his (limited) free time, Facundo enjoys a number of activities that include camping with his family, rock climbing, paddling, archery, photography and ham radio. 

Vasser Woolley Foundation Chair in Bioanalytical Chemistry
Professor; School of Chemistry and Biochemistry
Phone
404.385.4432
Office
ES&T L1244
Additional Research
Mass Spectrometry (MS) is one of the key analytical methods used to identify and characterize small quantities of biological molecules embedded in complex matrices. Although MS has found widespread use, improvements are still needed to extend its application to the grand challenges of this century. Since starting my position at Georgia Tech in 2004, my group members and I have used an integrated strategy with roots in bioanalytical chemistry, instrumentation development, bioinformatics, and theoretical modeling to focus on questions of great societal and scientific significance. To this purpose, we have integrated with cross-cutting teams devoted to problems that range from explaining the origins of life on Earth and diagnosing cancer at an early stage, to tracking the sources and prevalence of counterfeit pharmaceuticals worldwide. The common theme along these questions is the need for highly accurate tools for quantifying, identifying, and imaging trace chemicals in complex mixtures. Research in our lab uses state-of-the-art mass spectrometry, ion mobility gas-phase separations,ultrahigh performance liquid chromatography, and new soft ion generation techniques. We investigate the obtained data using machine learning and other powerful bioinformatic approaches. Our group is very dynamic, and each student pursues more than one project at a time, usually in collaboration with other group members or with other research groups at GT or elsewhere. Graduate and undergraduate students are trained in a variety of bioanalytical instrumentation/methodologies, with an emphasis on the fundamentals. We are analytical mass spectrometrists at heart, and strive to answer "big" scientific questions or questions with a large societal impact.
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Chemistry & Biochemistry

Flavio Fenton

Flavio Fenton
flavio.fenton@physics.gatech.edu
Professor
Phone
516-672-6003
Office
Howey N05
Additional Research
High performance computing: ·Development and implementation of novel algorithms to solve partial differential equations in two- and three-dimensional regular and irregular domains. ·Computer modeling of complex systems using supercomputers, as well as graphics cards (GPUs). ·Simulations and large data visualization of complex systems in or near-real time locally or over the web. Experiments in complex systems: ·Cardiac dynamics.Study the voltage and calcium dynamics of cardiac tissue using heart sections or whole hearts from fish and mice to large mamals horses. Using voltage- and calcium-sensitive dyes and ultrafast cameras, we record the dynamics of voltage and calcium waves and study their instabilities associated with arrhythmias. ·Dynamics of spiral and scroll waves. ·Mechanisms of bifurcation and period-doublings in time and in space. ·Methods for chaos control and synchronization. ·Chemical, physical, and other biophysical oscillators with complex dynamics and instabilities. Examples: spiral and scroll waves in the Belousov–Zhabotinsky reaction, saline oscillator. Mathematical modeling of complex systems: ·Development and analysis of mathematical models that describe generic or detailed dynamics of excitable and oscillatory media (heart, neurons, chemical reactions, calcium signaling, physical and biological oscillators, etc.). ·Study of bifurcations and chaotic (organized and disorganized) dynamics of excitable and oscillatory systems. ·Develop and apply control methods for suppressing or synchronizing complex dynamics. ·Study of stability and instabilities of spiral waves and three-dimensional scroll waves in idealized and realistic domains of excitable media. In most projects there is crossover between theory, simulations and experiments, where experiments (simulations) are used to guide theory and simulations (experiments).
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Affiliated Faculty
Data Engineering and Science
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Physics