Jaydev Desai

Jaydev Desai
jaydev@gatech.edu

Jaydev P. Desai, Ph.D, is currently a Professor and BME Distinguished Faculty Fellow in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech. Prior to joining Georgia Tech in August 2016, he was a Professor in the Department of Mechanical Engineering at the University of Maryland, College Park (UMCP). He completed his undergraduate studies from the Indian Institute of Technology, Bombay, India, in 1993. He received his M.A. in Mathematics in 1997, M.S. and Ph.D. in Mechanical Engineering and Applied Mechanics in 1995 and 1998 respectively, all from the University of Pennsylvania. He was also a Post-Doctoral Fellow in the Division of Engineering and Applied Sciences at Harvard University. He is a recipient of several NIH R01 grants, NSF CAREER award, and was also the lead inventor on the "Outstanding Invention of 2007 in Physical Science Category" at the University of Maryland, College Park. He is also the recipient of the Ralph R. Teetor Educational Award. In 2011, he was an invited speaker at the National Academy of Sciences "Distinctive Voices" seminar series on the topic of "Robot-Assisted Neurosurgery" at the Beckman Center. He was also invited to attend the National Academy of Engineering's 2011 U.S. Frontiers of Engineering Symposium. He has over 150 publications, is the founding Editor-in-Chief of the Journal of Medical Robotics Research, and Editor-in-Chief of the Encyclopedia of Medical Robotics (currently in preparation). His research interests are primarily in the area of image-guided surgical robotics, rehabilitation robotics, cancer diagnosis at the micro-scale, and rehabilitation robotics. He is a Fellow of the ASME and AIMBE.

Professor and Distinguished Faculty Fellow, Wallace H. Coulter Department of Biomedical Engineering
Associate Director, Institute for Robotics and Intelligent Machines
Director, Georgia Center for Medical Robotics
Phone
404.385.5381
Office
UA Whitaker Room 3112
Additional Research

Image-guided surgical robotics, Rehabilitation robotics; Cancer diagnosis at the micro-scale.

IRI and Role
Bioengineering and Bioscience > Faculty
Robotics > Core Faculty
Robotics
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering

James Dahlman

James Dahlman
james.dahlman@bme.gatech.edu

James Dahlman is a bioengineer / molecular engineer whose work lies at the interface of chemistry, nanotechnology, genomics, and gene editing. His lab focuses on targeted drug delivery, in vivo gene editing, Cas9 therapies, siRNA therapies, and developing new technologies to improve biomaterial design. 

The DahlmanLab is known for applying 'big data' technologies to nanomedicine. The lab is pioneering DNA barcoded nanoparticles; using DNA barcodes, >200 nanoparticles can be analyzed simultaneously in vivo. These nanoparticles are studied directly in vivo, and used to deliver targeted therapies like siRNA, mRNA, or Cas9. As a result of this work, James was named 1 of the 35 most innovative people under the age of 35 by MIT Technnology Review in 2018. James has won many national / international awards, and has published in Science, Nature Nanotechnology, Nature Biotechnology, Nature Cell Biology, Cell, Science Translational Medicine, PNAS, JACS, ACS Nano, Nano Letters, and other journals. James has also designed nanoparticles that efficiently deliver RNAs to the lung and heart. These nanoparticles can deliver 5 siRNAs at once in vivo, and are under consideration for clinical development. As a result, the lab has an interest in immunology and vascular biology. 

James supports entirely new research students come up with independently. To this end, DahlmanLab students learn how to (i) generate new ideas, (ii) select the good ones, and (iii) efficiently test whether the good ideas will actually work. 

Dahlman Lab students learn how to design/characterize/administer nanoparticles, how to isolate different cell types in vivo, how to rationally design DNA to record information, Cas9 therapies, and deep sequencing. As a result, the lab is an interdisciplinary group with students that have backgrounds in medicinal chemistry, BME, bioinformatics, biochemistry, and other fields. The lab welcomes students with all types of scientific backgrounds. The lab firmly stands by students, independent of their personal beliefs, preferences, or backgrounds.

Associate Professor
Phone
404-385-5262
Office
UAW 2101
Additional Research
In the Dahlman Lab, we focus on the interface between nanotechology, molecular biology, and genomics. We design drug delivery vehicles that target RNA and other nucleic acids to cells in the body. We have delivered RNAs to endothelial cells, and have treated heart disease, cancer, inflammation, pulmonary hypertension, emphysema, and even vein graft disease. Because we can deliver RNAs to blood vessels at low doses, sometimes we decide to deliver multiple therapeutic RNAs to the same cell at once. These 'multigene therapies' have been used to treat heart disease and cancer. Why is this important? Most diseases are caused by combinations of genes, not a single gene. We also rationally design the nucleic acids we want to deliver. For example, we re-engineered the Cas9 sgRNA to turn on genes, instead of turning them off. This enabled us to easily turn on gene A and turn off gene B in the same cell.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering

Ahmet Coskun

Ahmet Coskun
acoskun7@gatech.edu

Ahmet Coskun is a systems biotechnologist and bioengineer, working at the nexus of multiplex imaging and quantitative cell biology.

Single Cell Biotechnology Lab is strategically positioned for imaging one cell at a time for spatial context. We are multi-disciplinary researchers interested in photons, ions, and electrons and their interactions with cells and tissues.  Using large-scale experiments and computational analysis, we address fundamental challenges in cancers, immunology, and pediatric diseases. Variability of single cell profiles can be used to understand differences in therapeutic response, as well as satisfy our curiosity on understanding how cells are spatially organized in nature.

Our lab aims to deliver biotechnologies for spatial multi-omics profiling vision at the single cell level.

1) Spatial genomics: Our lab was part of an early efforts to demonstrate spatially resolved RNA profiling in single cells using a sequential FISH method. We will continue leveraging seqFISH and correlation FISH (another computational RNA imaging method) for exploring spatial dynamics of cellular societies.

2) Spatial proteomics: Our lab develops expertise on antibody-oligonucleotide based barcoding for multiplex protein imaging using CODEX technology. We combine CODEX with super-resolution and 3D imaging to visualize and quantify subcellular epigenetic states of immune and cancer cells.

3) Spatial metabolomics: Our lab works on computational and isotope barcoding approaches for small molecule profiling using MIBI (Multiplexed ion beam imaging). 3D and subcellular metabolic state of individual cells are used to model functional modes of cellular decision making in health and disease.

We also develop machine learning and deep learning algorithms to make sense of imaging based single cell big data.

In a nutshell, we create image-based ‘omic technologies to reveal spatial nature of biological systems. We benefit from enabler tools:  Super-resolution bioimaging, barcoded biochemical reagents, advanced algorithms and automated microfludics. Topical interests include Spatial Biology, Liquid Biopsy, and Global Oncology.

Ahmet Coskun trained at Stanford (Postdoc/Instructor with Garry Nolan), Caltech (Postdoc with Long Cai) and UCLA (PhD with Aydogan Ozcan). His lab is currently funded by NIH K25, BWF CASI, Georgia Tech & Emory.

Assistant Professor of Biomedical Engineering
Phone
404-894-3866
Office
Petit Biotechnology Building, Office 1311
Additional Research
The Single Cell Biotechnology Lab aims to study spatial biology in health and disease. Our research lies at the nexus of multiplex bioimaging, microfluidic biodynamics, and big data biocomputation. Using high-dimensional nanoscale imaging datasets, we address fundamental challenges in immuno-engineering, cancers, and pediatric diseases. Our lab pursues a transformative multi-omics technology to integrate spatially resolved epigenetics and spatial genomics, proteomics, and metabolomics, all in the same platform. We uniquely benefit from super-resolution microscopy, imaging mass spectrometry, combinatorial molecular barcoding, and machine learning to enhance the information capacity of our cellular data. Variability of single cell images can be used to understand differences in therapeutic responses, as well as satisfy our curiosity on understanding how cells are spatially organized in nature.
IRI and Role
Bioengineering and Bioscience > Faculty
Data Engineering and Science > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology

Julie Champion

Julie Champion
julie.champion@chbe.gatech.edu

Julie Champion is the William R. McLain Endowed Term Professor in the School of Chemical and Biomolecular Engineering at Georgia Institute of Technology. She earned her B.S.E. in chemical engineering from the University of Michigan and Ph.D. in chemical engineering at the University of California Santa Barbara. She was an NIH postdoctoral fellow at the California Institute of Technology. Champion is a fellow of the American Institute for Medical and Biological Engineering and has received awards including American Chemical Society Women Chemists Committee Rising Star, NSF BRIGE Award, Georgia Tech Women in Engineering Faculty Award for Excellence in Teaching, Georgia Tech BioEngineering Program Outstanding Advisor Award. Professor Champion’s current research focuses on design and self-assembly of functional nanomaterials made from engineered proteins for applications in immunology, cancer, and biocatalysis.

Professor, School Chemical and Biomolecular Engineering
Phone
404.894.2874
Office
EBB 5015
Additional Research

Cellular Materials; Drug Delivery; Self-Assembly; "Developing therapeutic protein materials, where the protein is both the drug and thedelivery system Engineering proteins to control and understand protein particleself-assembly Repurposing and engineering pathogenic proteins for human therapeutics Creating materials that mimic cell-cell interactions to modulate immunologicalfunctions for various applications, including inflammation, cancer, autoimmune disease, and vaccination"

IRI and Role
Bioengineering and Bioscience > Faculty
Matter and Systems > Affiliated Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > School of Chemical and Biomolecular Engineering
Research Areas
Matter and Systems
  • Computing and Communication Technologies
  • Human-Centric Technologies

Pamela Bhatti

Pamela Bhatti
pamela.bhatti@ece.gatech.edu

Dr. Pamela Bhatti is Professor and Associate Chair for Strategic Initiatives and Innovation at the School of Electrical and Computer Engineering, Georgia Tech. Her research is dedicated to overcoming sensory loss in human hearing through focused neural stimulation, and novel implantable sensors. Dr. Bhatti also conducts research in cardiac imaging to assess and monitor cardiovascular disease. She received her B.S. in Bioengineering from the University of California, Berkeley (1989), her M.S. in Electrical Engineering from the University of Washington (1993), and her Ph.D. in Electrical Engineering from the University of Michigan, Ann Arbor (2006). In 2013, she earned an M.S. in Clinical Research from Emory University, and co-founded a startup company (Camerad Technologies) based on her research in detecting wrong-patient errors in radiology. Dr. Bhatti is the IEEE Journal of Translational Engineering in Health and Medicine, Editor-in-Chief; and, in 2017, received the Georgia Tech Class of 1934 Outstanding Interdisciplinary Activities Award.

Assistant Professor
Phone
404-894-7467
Office
MiRC 225
Additional Research

Biomedical sensors and subsystems including bioMEMS Neural prostheses: cochlear and vestibular Vestibular rehabilitation

IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
Matter and Systems
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > School of Electrical and Computer Engineering

Paul Benkeser

Paul Benkeser
pbenkeser@gatech.edu

Paul Benkeser is a professor and senior associate chair in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University. A member of the Georgia Tech faculty since 1985, he was one of the founding faculty of the Coulter Department in 1998 and served as its first associate chair for undergraduate studies.    

His early research interests were in therapeutic and diagnostic applications of ultrasound. After joining the Coulter Department he redirected his energies toward enhancing undergraduate biomedical engineering  education, with particular interests in integrating problem-driven learning and global experiential learning opportunities in the curriculum. His research and education endeavors have been funded by grants from NIH, NSF, the Department of Veterans Affairs, and the Whitaker Foundation.    

Dr. Benkeser has been active in engineering accreditation activities for ABET since 2002, serving in a number of capacities including program evaluator, EAC Commissioner, and member of its board of delegates. He is a member of the American Institute for Medical and Biological Engineering, Biomedical Engineering Society, and American Society for Engineering Education, and a senior member of the Institute of Electrical and Electronics Engineers.    

He received his BS from Purdue University and MS and PhD from the University of Illinois at Urbana-Champaign, all in electrical engineering.

Professor
Senior Associate Chair
Phone
404-894-2912
Office
UAW 2125
Additional Research
Ultrasonic bioengineering, biomedical signal and image processing, and biomedical engineering education.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering