Young-sup Yoon

Young-sup Yoon
yyoon5@emory.edu

The Yoon Lab has been working on stem cell research in various cardiovascular diseases. Our major research interest is to use stem cell technology to treat various cardiovascular diseases, and we have been developing and using different bone marrow-derived stem sell or progenitor cells for cardiovascular repair.

Professor of Medicine
Director of Stem Cell Biology
Phone
404-727-8176
Office
Emory WMRB 3309
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University > Division of Cardiology

Younan Xia

Younan Xia
younan.xia@bme.gatech.edu

Xia is the Brock Family Chair and Georgia Research Alliance (GRA) Eminent Scholar in Nanomedicine in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University, with joint appointments in School of Chemistry and Biochemistry, and School of Chemical and Biomolecular Engineering. Professor Xia received his Ph.D. degree in Physical Chemistry from Harvard University (with Professor George M. Whitesides) in 1996, his M.S. degree in Inorganic Chemistry from University of Pennsylvania (with the late Professor Alan G. MacDiarmid, a Nobel Laureate in Chemistry, 2000) in 1993, and his B.S. degree in Chemical Physics from the University of Science and Technology of China (USTC) in 1987. He came to the United States of America in 1991. Xia has received a number of prestigious awards, including the 2013 Nano Today Award, the ACS National Award in the Chemistry of Materials (2013), Fred Kavli Distinguished Lecture in Nanoscience at the MRS Spring Meeting (2013), AIMBE Fellow (2011), MRS Fellow (2009 ), NIH Director's Pioneer Award (2006), ACS Leo Hendrik Baekeland Award (2005), Camille Dreyfus Teacher Scholar (2002), David and Lucile Packard Fellowship in Science and Engineering (2000), Alfred P. Sloan Research Fellow (2000), NSF Early Career Development Award (2000), ACS Victor K. LaMer Award (1999), and Camille and Henry Dreyfus New Faculty Award (1997). Xia has been an Associate Editor of Nano Letters since 2002, and has served on the Advisory Boards of Particle & Particle Systems Characterization (2013-), Chemical Physics Letters (2013-), Chemistry: A European Journal (2013-), Chinese Journal of Chemistry (2013-), Angewandte Chemie International Edition (2011-), Advanced Healthcare Materials (2011-, inaugural chairman of the advisory board), Accounts of Chemical Research (2010-), Cancer Nanotechnology (2010-), Chemistry: An Asian Journal (2010-), Journal of Biomedical Optics (2010-), Nano Research (2009-), Science of Advanced Materials (2009-), Nano Today (2006-), Chemistry of Materials (2005-2007), Langmuir (2005-2010, 2013-2015), International Journal of Nanotechnology (2004-), and Advanced Functional Materials (2001-). He has also served as a Guest Editor of special issues for Advanced Materials (six times), Advanced Functional Materials (one time), MRS Bulletin (one time), and Accounts of Chemical Research (one time).

GRA Eminent Scholar in Nanomedicine, Wallace H. Coulter Department of Biomedical Engineering
Professor, Wallace H. Coulter Department of Biomedical Engineering
Brock Family Chair, Wallace H. Coulter Department of Biomedical Engineering
Professor, School of Chemistry and Biochemistry, and School of Chemical and Biomolecular Engineering
Phone
404.385.3209
Office
MSE 3100J
Additional Research
Catalysis; Nanomedicine; Bio-Inspired Materials; Tissue Engineering
IRI and Role
Bioengineering and Bioscience > Faculty
Matter and Systems > Affiliated Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering

Levi Wood

Levi Wood
levi.wood@me.gatech.edu

Dr. Wood completed his graduate training at the Massachusetts Institute of Technology. While there he worked under the guidance of Drs. H. Harry Asada and Roger Kamm to develop and use microfluidics to identify mechanisms governing vascular geometry. 

During his postdoc, Dr. Wood worked under Dr. Kevin Haigis (Beth Israel Deaconess Medical Center and Harvard Medical School) and Dr. Douglas Lauffenburger (Massachusetts Institute of Technology) to use systems biology to identify novel signaling mechanisms driving neuronal death in Alzheimer's disease and epithelial cell death during intestinal inflammation.

Associate Professor
Phone
404-385-4465
Office
Petit Biotechnology Building, Office 3303
Additional Research
Our research focuses on applying systems analysis approaches and engineering tools to identify novel clinical therapeutic targets for complex diseases. It is challenging to develop new treatments for these diseases, such as Alzheimer's disease(AD) and Traumatic Brain Injury (TBI), because they do not have a single genetic cause and they simultaneously present broad physiologic changes. By combining novel engineeredin vitroplatforms, mouse models, and multivariate computational systems analysis, we will be able to 1) capture a holistic systems-level understanding of complex diseases, and 2) isolate specific mechanisms driving disease. The ultimate goal of our laboratory is to use these tools to identify new mechanisms driving disease onset and progression that will translate to effective therapeutic strategies.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Edmund Waller

Edmund Waller
ewaller@emory.edu

Dr. Waller specializes in bone marrow transplants for acute leukemia, myelodysplastic syndrome, myeloproliferative neoplasms, lymphoma, aplastic anemia, sickle cell disease and in the management of graft-versus-host disease.

Professor of Medicine, Medical Oncology and Pathology
Rein Saral Professor of Cancer Medicine
Interim Associate Director, Clinical Research, Winship Cancer Institute
Medical Director, Center for Stem Cell Processing and Apheresis
Director, Emory Regenerative Engineering and Medicine Center
Phone
404-778-2984
Office
Winship Cancer Institute of Emory University
Additional Research
Dr. Waller's research focus is in enhancing immune reconstitution after stem cell transplant and developing cell and small-molecule based cancer immunotherapeutics. His current research activities include pre-clinical and clinical studies focused on the role of donor immune cells in optimizing anti-tumor immunity after allogenic transplantation, enhancing functional properties of chimeric-antigen-receptor T cells, and blocking novel immune check-point pathways in cancer. His NIH-funded basic and translational research lab uses mouse models and performs immunological analyses of clinical samples from patients. He has active translational research activities and serves as a principal investigator on institutional and national cooperative group clinical trials.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University > Department of Hematology and Medical Oncology

Susan Thomas

Susan Thomas
susan.thomas@gatech.edu

Susan Napier Thomas holds the Woodruff Professorship and is a Professor (full) with tenure of Mechanical Engineering in the Parker H. Petit Institute of Bioengineering and Bioscience at the Georgia Institute of Technology where she holds adjunct appointments in Biomedical Engineering and Biological Science and is a member of the Winship Cancer Institute of Emory University. Prior to this appointment, she was a Whitaker postdoctoral scholar at École Polytechnique Fédérale de Lausanne (one of the Swiss Federal Institutes of Technology) and received her B.S. in Chemical Engineering with an emphasis in Bioengineering cum laude from the University of California Los Angeles and her Ph.D. in Chemical & Biomolecular Engineering Department as a NSF Graduate Research Fellow from The Johns Hopkins University. For her contributions to the emerging field of immunoengineering, she has been honored with the 2022 Award for Young Investigator from Elsevier's journal Biomaterials for "outstanding contributions to the field" of biomaterials science, the 2018 Young Investigator Award from the Society for Biomaterials for "outstanding achievements in the field of biomaterials research" and the 2013 Rita Schaffer Young Investigator Award from the Biomedical Engineering Society "in recognition of high level of originality and ingenuity in a scientific work in biomedical engineering." Her interdisciplinary research program is supported by multiple awards on which she serves as PI from the National Cancer Institute, the Department of Defense, the National Science Foundation, and the Susan G. Komen Foundation, amongst others.

Professor
Associate Director, Integrated Cancer Research Center
Co-Director, Regenerative Engineering and Medicine Research Center
Phone
404-385-1126
Office
Petit Biotechnology Building, Office 2315
Additional Research
Thomas's research focuses on the role of biological transport phenomena in physiological and pathophysiological processes. Her laboratory specializes in incorporating mechanics with cell engineering, biochemistry, biomaterials, and immunology in order to 1) elucidate the role mechanical forces play in regulating seemingly unrelated aspects of tumor progression such as metastasis and immune suppression as well as 2) develop novel immunotherapeutics to treat cancer. Cancer progression is tightly linked to the ability of malignant cells to exploit the immune system to promote survival. Insight into immune function can therefore be gained from understanding how tumors exploit immunity. Conversely, this interplay makes the concept of harnessing the immune system to combat cancer an intriguing approach. Using an interdisciplinary approach, we aim to develop a novel systems-oriented framework to quantitatively analyze immune function in cancer. This multifaceted methodology to study tumor immunity will not only contribute to fundamental questions regarding how to harness immune response, but will also pave the way for novel engineering approaches to treat cancer such as with vaccines and cell- or molecular-based therapies.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Johnna Temenoff

Johnna Temenoff
johnna.temenoff@bme.gatech.edu

Dr. Johnna S. Temenoff is the Carol Ann and David D. Flanagan Professor at the Coulter Department of Biomedical Engineering at Georgia Tech/Emory University. She is also currently the Director of the NSF Engineering Research Center in Cell Manufacturing Technologies (CMaT) and the Director of the Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M). Scientifically, Dr. Temenoff is interested in scaling culture of therapeutic cells and tailoring the molecular interactions between glycosaminoglycans and proteins/cells for use in regenerative medicine applications.  Her laboratory focuses primarily on promoting repair after injuries to the tissues of the shoulder, including cartilage, tendon, and muscle.

Dr. Temenoff has been honored with several prestigious awards, such as the NSF CAREER Award, Arthritis Foundation Investigator Award, and Society for Biomaterials (SFB) Clemson Award for Contributions to the Literature, and was named to the College of Fellows of the American Institute for Medical and Biological Engineers (AIMBE), as a Fellow of the Biomedical Engineering Society (BMES), as a Fellow of the International Academy of Medical and Biological Engineering (IAMBE) and as a Fellow of Biomaterials Science and Engineering, International Union of Societies for Biomaterials Science and Engineering (IUSBSE).  She has co-authored a highly successful introductory textbook - Biomaterials: The Intersection of Biology and Materials Science, by J.S. Temenoff and A.G. Mikos (now in a 2nd edition), for which Dr. Temenoff and Dr. Mikos were awarded the American Society for Engineering Education’s Meriam/Wiley Distinguished Author Award for best new engineering textbook. 

Carol Ann and David D. Flanagan Professorship II
Director, NSF Engineering Research Center for CMaT
Marcus Center for Therapeutic Cell Characterization and Manufacturing (MC3M)
Phone
404-385-5026
Office
Petit 2305
IRI and Role
Bioengineering and Bioscience > Faculty
Matter and Systems > Affiliated Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering
Research Areas
Matter and Systems
  • Human-Centric Technologies

Mark Styczynski

Mark Styczynski
mark.styczynski@chbe.gatech.edu

Mark Styczynski is an Associate Professor in the School of Chemical & Biomolecular Engineering at the Georgia Institute of Technology (Georgia Tech), doing research at the interface of synthetic and systems biology as applied to metabolic systems. His synthetic biology work focuses on the development of low-cost, minimal-equipment biosensors for the diagnosis of nutritional deficiencies in the developing world. His systems biology work uses computational and experimental methods to characterize metabolic dynamics and regulation using metabolomics data. He has received young investigator awards from the NSF, DARPA, and ORAU. He has won multiple department-and institute-level teaching awards at Georgia Tech. He founded and was the first president of the Metabolomics Association of North America (MANA), and is a Council Member in the Engineering BiologyResearch Consortium.

Professor
Phone
404-894-2825
Office
EBB 4013
Additional Research
Modelling and controlling metabolic dynamics and regulation (metabolic engineering). Biofuels. Systems biology-based experimental and bioinformatics analysis of metabolism Synthetic biology for the development of biosensors and diagnostics The main focus of theStyczynski groupis the experimental and computational study of the dynamics and regulation of metabolism, with ultIMaTe applications in metabolic engineering, biotechnology, and biosensors/diagnostics.
IRI and Role
Bioengineering and Bioscience > Faculty
Energy > Research Community
Bioengineering and Bioscience
Energy
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > School of Chemical and Biomolecular Engineering

Steve Stice

Steve Stice
sstice@uga.edu

Steve Stice is Co-Founder and Chief Scientific Officer of ArunA Biomedical, Inc, where he directs the company’s clinical and research operations. He is also University of Georgia, DW Brooks Distinguished Professor and Director of the Regenerative Bioscience Center, and holds a Georgia Research Alliance Eminent Scholar endowed chair. 

Prior to joining ArunA, Stice was the co-founder and served as both Chief Scientific Officer and Chief Executive Officer of Advanced Cell Technology, the first U.S. company to advance to human clinical trials using human pluripotent stem cells. He also co-founded startups Prolinia and Cytogenesis, the latter of which has since merged with ViaCyte. 

Stice was recruited to the University of Georgia by the Georgia Research Alliance (GRA) and holds an endowed chair as a GRA Eminant Scholar. Additionally, Stice serves as the Director of the Univeristy of Georgia’s Regenerative Bioscience Center, co-directs The Regenerative Engineering and Medicine Research Center (REM), a joint collaboration between Emory University, Georgia Institute of Technology and UGA, is a group leader of Emergent Behaviors of Integrated Cellular Systems, a National Science Foundation Center founded by the Massachusetts Institute of Technology. Stice also sits on the toxicology Scientific Advisory Board for the Food and Drug Administration (FDA). 

Stice received a Masters of Science in Reproductive Biology from Iowa State University and a Doctor of Philosophy, Developmental Biology and Embryology, from the University of Massachusetts.

D.W. Brooks Distinguished Professor
Co-Director, Regenerative Engineering and Medical Center (REM)
Director, UGA Regenerative Bioscience Center
Georgia Research Alliance Eminent Scholar
Phone
706-583-0071
Additional Research
Finding new treatments for degenerative diseases such Parkinson's, Alzheimer's and Multiple Sclerosis andneural injuries spinal cord and head trauma as well as treating cardiovascular diseases (heart and blood vessel repair) through stem cell technologies. Animal stem cells and cloning animal agriculture, veterinary and biomedicine applications.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
University of Georgia > Department of Animal and Dairy Science

Stephen Sprigle

Stephen Sprigle
stephen.sprigle@design.gatech.edu

Stephen Sprigle is a Professor at the Georgia Institute of Technology with appointments in Bioengineering, Industrial Design and the George W. Woodruff School of Mechanical Engineering. 

A biomedical engineer with a license in physical therapy, Sprigle directs the Rehabilitation Engineering and Applied Research Lab (REARLab), which focuses on applied disability research and development. The REARLab’s research interests include the biomechanics of wheelchair seating and posture, pressure ulcer prevention, and manual wheelchair propulsion. Its development activities include standardized wheelchair and cushion testing and the design of assistive and diagnostic technologies. Sprigle teaches design-related classes in both the Schools of Industrial Design and Mechanical Engineering.

Professor
Phone
404-385-4302
Office
Architecture 0155
Additional Research
Applied research and device development targeting the increased heath and function of persons with disabilities. Specific areas of interest include: wheeled mobility and seating, pressure ulcer prevention and treatment; design of diagnostic tissue interrogation devices; design of assistive technology. Wheeled Mobility and Seating; Pressure Ulcer Prevention and Treatment; Design of Diagnostic Tissue Interrogation Devices; Design of Assistive Technologies
IRI and Role
Bioengineering and Bioscience > Faculty
People and Technology > Affiliated Faculty
People and Technology
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering
Georgia Institute of Technology > College of Design > School of Industrial Design

Krishnendu Roy

Krishnendu Roy
krish.roy@gatech.edu

 In August 2023, Krishnendu Roy joined Vanderbilt University as the Bruce and Bridgitt Evans Dean of Engineering and a University Distinguished Professor in Biomedical Engineering, and Pathology, Microbiology, and Immunology, with a secondary appointment in Chemical and Biomolecular Engineering.

Previously, Roy served as Robert A. Milton Endowed Chair for the Coulter Department of Biomedical Engineering at Georgia Tech. He is also the former Director of the NSF Engineering Research Center (ERC) for Cell Manufacturing Technologies (CMaT), Center for ImmunoEngineering at Georgia Tech, and Marcus Center for Therapeutic Cell Characterization and Manufacturing. 

His overall research interests are in developing novel concepts for stem cell engineering as well as polymer controlled delivery of biological factors, especially for nucleic acid therapeutics (DNA, SiRNA and oligos) and immunoengineering. Currently, his group is involved in the following major areas of research; (a) Developing novel concepts to produce biodegradable surface functionalized micro-and nanoparticles for targeted and sustained delivery of nucleic acids, proteins, peptides and other immune modulators. In particular he is interested in developing multi-agent vaccine delivery systems for cancer and infectious diseases as well as immunotherapies for autoimmune diseases. (b) Creating spatio-temporally patterned polymer scaffolds for directed compartmental differentiation of stem cells into multiple lineages. (c) Engineering an artificial thymic niche for directed differentiation of stem cells into functional, antigen- specific T cells. (e) The development of novel nanoimprinting techniques to generate shape specific, environmentally triggered drug nanocarriers.

Faces of Research - Profile Article

Bruce and Bridgitt Evans Dean of Engineering at Vanderbilt University
University Distinguished Professor
Professor of Biomedical Engineering
Professor of Pathology, Microbiology and Immunology
Professor of Chemical and Biomolecular Engineering
Phone
404.385.6166
Additional Research
The overall goal of our research endeavor is the development of new biomaterial-based strategies for gene/drug delivery and stem cell engineering. Towards this, my laboratory focuses on three major directions: (a) design and development of novel delivery systems for nucleic-acid based immunotherapy and cancer chemotherapy (b) engineering complex microenvironments to study and manipulate stem cells and understand their behavior in biomimetic, three-dimensional conditions and (c) developing novel engineering tools and high throughput methods to generate functional T cells and Dendritic cells from stem cells.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering