Todd Sulchek

Todd Sulchek
todd.sulchek@me.gatech.edu

Todd Sulchek is an associate professor in Mechanical Engineering at Georgia Tech where he conducts fundamental and applied research in the field of biophysics. His research program focuses on the mechanical and adhesive properties of cell and biological systems and the development of microsystems to aid in their study. His research employs tools, including, MEMS, microfluidics, imaging, and patterning to understand or enable biological systems. His interests include cancer diagnostics, stem cell biomanufacturing, novel therapeutics, and ultracheap engineering tools. He is a member of the interdisciplinary Institute for Bioengineering and Bioscience. Dr. Sulchek also holds program faculty positions in Bioengineering and Biomedical Engineering and has a courtesy appointment in the School of Biology. He received his Ph.D. from Stanford in Applied Physics under Calvin Quate and received a bachelors in math and physics from Johns Hopkins. He was a postdoc and staff scientist at Lawrence Livermore National Lab. He joined Georgia Tech in 2008 as an Assistant Professor of Mechanical Engineering. He is a recipient of the NSF CAREER award, the BP Junior Faculty Teaching Excellence Award, the Lockheed Inspirational Young Faculty award, and the 2012 Petit Institute Above and Beyond Award. To date he has published 42 journal papers and has filed or been issued 7 patents. Prof. Sulchek is a strong supporter of undergraduate research, and he participates in a variety of undergraduate education activities including the Undergraduate Research Opportunities Program (UROP) and includes over 8 undergraduate authors in the past year.

Professor, Woodruff School of Mechanical Engineering
Appointments in Bioengineering, Biomedical Engineering, and Biology
Phone
404.385.1887
Office
Petit 2309
Additional Research

Biomedical Devices; bio-MEMS; biosensors; Drug Delivery; Advanced Characterization. Dr. Sulchek's research focuses primarily on the measurement and prediction of how multiple individual biological bonds produce a coordinated function within molecular and cellular systems. There are two complementary goals. The first is to understand the kinetics of multivalent pharmaceuticals during their targeting of disease markers; the second is to quantify the host cell signal transduction resulting from pathogen invasion. Several tools are developed and employed to accomplish these goals. The primary platform for study is the atomic force microscope (AFM), which controls the 3-D positioning of biologically functionalized micro- and nanoscale mechanical probes. Interactions between biological molecules are quantified in a technique called force spectroscopy. Membrane protein solubilized nanolipoprotein particles (NLPs) are also used to functionalize micro/nano-scale probes with relevant biological mediators. This scientific program requires the development of enabling instrumentation and techniques, which include the following: Advanced microscopy and MEMs; Nanomechanical linkers, which provide a convenient platform to control biomolecular interactions and study multivalent molecular kinetics; Biological mimetics, which provide a simple system to study cell membranes and pathogens. UltIMaTely, this work is used to optimize molecular drug targeting, improve chem/bio sensors, and develop more efficient pathogen countermeasures.

IRI and Role
Bioengineering and Bioscience > Faculty
Renewable Bioproducts > Faculty
Bioengineering and Bioscience
Renewable Bioproducts
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Chengzhi Shi

Chengzhi Shi
chengzhi.shi@me.gatech.edu

Dr. Shi joined Georgia Tech in August 2018 as an assistant professor. Prior, he worked as a graduate student researcher at the Department of Mechanical Engineering of the University of California, Berkeley and Materials Science Division of Lawrence Berkeley National Laboratory focusing on the study of acoustic angular momentum and the design and realization of acoustic metamaterials and high-speed acoustic communication. His Ph.D. dissertation (2018) focuses on the development of acoustic metamaterials and the physics of the angular momentum of sound. Prior to his Ph.D. study at the Department of Mechanical Engineering of the University of California, Berkeley, Dr. Shi completed his M.S. degree in mechanical engineering at the University of Michigan-Shanghai Jiao Tong University Joint Institute in Shanghai, China. His M.S. thesis (2013) focuses on the dynamics and vibration of cyclically symmetric rotating mechanical systems.

Assistant Professor
Phone
404-894-2558
Office
003 Love Manufacturing Building
Additional Research
Acoustic wave interactions with different cells including neurons, and imaging and treatment techniques resulted from the interactions.
IRI and Role
Bioengineering and Bioscience > Faculty
Energy > Research Community
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering

Ingeborg Schmidt-Krey

Ingeborg Schmidt-Krey
ingeborg.schmidt-krey@biosci.gatech.edu

Ingeborg Schmidt-Krey is an associate professor in the School of Biological Sciences at Georgia Tech. Her research interests lie in the structure and function of eukaryotic membrane proteins, two-dimensional crystallization, electron crystallography, single particle analysis, and electron cryo-microscopy (cryo-EM).

Associate Professor
Phone
404-385-0286
Office
Cherry Emerson A118
Additional Research
Eukaryotic membrane proteins comprise approximately 60% of all drug targets and are consequently immensely important for biomedical research. Despite their importance, only few could thus far be studied at the structural level. My research focuses on the crystallization, structure and function of eukaryotic membrane proteins. Electron crystallography is the main tool employed to study these proteins in my laboratory. Initially, this involves testing of conditions for growing two-dimensional (2D) crystals, usually by reconstituting the detergent-solubilized membrane protein into a bilayer. Once crystallization parameters have been identified by electron microscopy of negatively stained samples, electron cryo-microscopy is employed to collect high-resolution data. The structure is then obtained by image processing. The approach of 2D crystallization and electron crystallography is particularly suitable for highly fragile membrane proteins such as many eukaryotic ones. Reconstitution ensures an environment that is close to the native one, the detergent is removed, and functional studies are relatively easily undertaken. Experimental phases are obtained due to the fact that images are collected. In some instances the image amplitudes can be substituted with electron diffraction amplitudes. Although electron crystallographic methods are well developed, little is known about the factors important in 2D crystallization, and screening protocols as for 3D crystallization do not exist. An important aspect of my research interests aims at developing screening methods and strategies for 2D crystallization and at understanding the underlying mechanisms.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Khalid Salaita

Khalid Salaita
k.salaita@emory.edu

Khalid Salaita is the Samuel Candler Dobbs Professor of Chemistry, and Director for Graduate Studies in the Chemistry Department at Emory University in Atlanta, Georgia (USA). Khalid grew up in Jordan and moved to the US in 1997 to pursue his undergraduate studies at Old Dominion University in Norfolk, Virginia (USA). He worked under the mentorship of Prof. Nancy Xu studying the spectroscopic properties of plasmonic nanoparticles. He then obtained his Ph.D. with Prof. Chad Mirkin at Northwestern University (Evanston, IL) in 2006. 

During that time, he studied the electrochemical properties of organic adsorbates patterned onto gold films and developed massively parallel scanning probe lithography approaches. From 2006-2009, Khalid was a postdoctoral scholar with Prof. Jay T. Groves at the University of California at Berkeley (USA) where he investigated the role of receptor clustering in modulating cell signaling. In 2009, Khalid started his own lab at Emory University, where he is currently investigating the use of nucleic acids as molecular force sensors, smart drugs, and synthetic motors. 

In recognition of his independent work, Khalid has received a number of awards, most notably: the Alfred P. Sloan Research Fellowship, the Camille-Dreyfus Teacher Scholar award, the National Science Foundation Early CAREER award, the Kavli Fellowship, and Merck Future Insight Prize. Khalid is currently the director of the Center on Probes for Molecular Mechanotechnology, and an Associate Editor of SmartMat. Khalid’s program has been supported by NSF, NIH, and DARPA.

Associate Professor
Samuel Candler Dobbs Professor of Chemistry
Director for Graduate Studies in the Chemistry Department
Program Faculty in the Department of Biomedical Engineering at Emory University and Georgia Institute of Technology
Phone
404-727-7522
Office
506 Atwood
Additional Research
In 2009, Khalid started his own lab at Emory University, where he currently investigates biophysical aspects of receptor-mediated cell signaling. To achieve this goal, his group has pioneered the development of molecular force probes and nano-mechanical actuators that are integrated with living cells. These materials are used to investigate the molecular mechanisms of a number of pathways where piconewton forces are thought to be important. These pathways include the Notch-Delta pathway, T cell receptor activation and the integrin-based focal adhesion pathway.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University > Department of Chemistry

Frank Rosenzweig

Frank Rosenzweig
frank.rosenzweig@biology.gatech.edu

Frank Rosenzweig is a Professor in School of Biological Sciences. He holds Bachelors degrees in Comparative Literature and Zoology from University of Tennessee-Knoxville, and a PhD in Biology at University of Pennsylvania. He carried out postdoctoral studies at the University of Michigan. He was a professor at University of Idaho, University of Florida, and University of Montana before joining the Georgia Tech faculty in 2016. He served as the Director of the NASA Astrobiology Institute funded center “Reliving the Past” from 2015 to 2019.  His research group studies the ecological and evolutionary forces that produce and preserve genetic variation using experimental evolution  to illuminate how genetic variation maps onto organismal fitness.

Professor
Phone
404-385-4458
Office
EBB 2007
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Felipe Garcia Quiroz

Felipe Garcia Quiroz

Felipe trained as a biomedical engineer in his native Colombia before obtaining a PhD from the Biomedical Engineering department of Duke University. At Duke, working in the laboratory of Ashutosh Chilkoti, he focused on the engineering of genetically-encoded, self-assembling protein polymers. An important outcome of this PhD work was the elucidation of sequence rules to program the phase separation behavior of intrinsically disordered proteins (IDPs). Motivated by a newly acquired ability to engineer the phase behavior of IDPs, for his postdoctoral work he turned to their poorly-understood biology. To pursue skin as an outstanding biological system, Felipe joined the group of Elaine Fuchs at Rockefeller University. Felipe’s postdoctoral research led to the discovery that liquid-liquid phase separation drives the process of skin barrier formation. In 2020, he established the Quiroz Lab in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, where he is currently an Assistant Professor. Felipe is the recipient of multiple research awards, including a Career Award at the Scientific Interface from the Burroughs Wellcome Fund and the NIH Director’s New Innovator Award.

Assistant Professor
Phone
404-251-5435
Office
Health Sciences Research Building, Room E184 (Emory)
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Coulter Department of Biomedical Engineering

H. Jerry Qi

H. Jerry Qi
qih@me.gatech.edu

H. Jerry Qi is a professor and the Woodruff Faculty Fellow in the George W. Woodruff School of Mechanical Engineering at Georgia Institute of Technology. He received his bachelor degrees (dual degree), master and Ph.D. degree from Tsinghua University (Beijing, China) and a ScD degree from Massachusetts Institute of Technology (Boston, MA, USA). After one year postdoc at MIT, he joined University of Colorado Boulder as an assistant professor in 2004, and was promoted to associate professor with tenure in 2010. He joined Georgia Tech in 2014 as an associate professor with tenure and was promoted to a full professor in 2016. Qi is a recipient of NSF CAREER award (2007). He is a member of Board of Directors for the Society of Engineering Science. In 2015, he was elected to an ASME Fellow. The research in Qi's group is in the general area of soft active materials, with a focus on 1) 3D printing of soft active materials to enable 4D printing methods; and 2) recycling of thermosetting polymers. The material systems include: shape memory polymers, light activated polymers, vitrimers. On 3D printing, they developed a wide spectrum of 3D printing capability, including: multIMaTerial inkjet 3D printing, digit light process (DLP) 3D printing, direct ink write (DIW) 3D printing, and fused deposition modeling (FDM) 3D printing. These printers allow his group to develop new 3D printing materials to meet the different challenging requirements. For thermosetting polymer recycling, his group developed methods that allow 100% recycling carbon fiber reinforced composites and electronic packaging materials. Although his group develops different novel applications, his work also relies on the understanding and modeling of material structure and properties under environmental stimuli, such as temperature, light, etc, and during material processing, such as 3D printing. Constitutive model developments are typically based on the observations from experiments and are then integrated with finite element through user material subroutines so that these models can be used to solve complicated 3D multiphysics problems involving nonlinear mechanics. A notable example is their recent pioneer work on 4D printing, where soft active materials is integrated with 3D printing to enable shape change (or time in shape forming process). Recently, his developed a state-of-the-art hybrid 3D printing station, which allows his group to integrate different polymers and conduct inks into one system. Currently, his group is working on using this printing station for a variety of applications, including printed 3D electronics, printed soft robots, etc.

Professor, Woodruff School of Mechanical Engineering
Woodruff Faculty Fellow, Woodruff School of Mechanical Engineering
Phone
404.385.2457
Office
MRDC 4104
Additional Research

Additive/Advanced Manufacturing; micro and nanomechanics; Recycling; Soft Materials; Conducting Polymers

IRI and Role
Bioengineering and Bioscience > Faculty
Renewable Bioproducts > Faculty
Matter and Systems > Affiliated Faculty
Bioengineering and Bioscience
Renewable Bioproducts
University, College, and School/Department
Georgia Institute of Technology > College of Engineering > Woodruff School of Mechanical Engineering
Research Areas
Matter and Systems
  • Frontiers in Infrastructure

Boris Prilutsky

Boris Prilutsky
boris.prilutsky@biosci.gatech.edu

The research focus of Boris Prilutsky's laboratory is Neural Control and Biomechanics of Movement. They study how the nervous system controls hundreds of muscles and kinematic degrees of freedom of the body to produce purposeful motor behaviors and how the neural control of motor behaviors is affected by neural and musculoskeletal injuries.

Professor
Phone
404-894-7659
Office
MSPO Program 1309D
Additional Research
The major research focus of my research is on biomechanics and motor control of locomotion and reaching movements in normal as well as in neurological and musculoskeletal pathological conditions. In particular, we study the mechanisms of sensorimotor adaptation to novel motor task requirements caused by visual impairament, peripheral nerve or spinal cord injury, and amputation. We also investigate how motor practice and sensory information affect selections of adaptive motor strategies.
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Georgia Institute of Technology > College of Sciences > School of Biological Sciences

Jay Patel, Ph.D.

Jay Patel, Ph.D.
jay.milan.patel@emory.edu

Jay Patel, Ph.D., is an Assistant Professor in the Department of Orthopaedics at Emory and a Health Science Specialist at the Atlanta VA. Patel joined the faculty at Emory in September 2020, and his program focuses on the repair and regeneration of musculoskeletal tissues (e.g., cartilage, meniscus), with an emphasis on using micro-scale findings to drive macro-scale therapies. His lab uses a combination of biomechanics, biomaterials, mechano-biology, in vitro systems, and functional in vivo models to motivate, design, develop, and evaluate novel treatments and therapeutics for orthopaedic injuries. He received his Bachelor’s in Bioengineering from Rice University and his Ph.D. in Biomedical Engineering from Rutgers University. He then pursued his postdoctoral training at the University of Pennsylvania in the Department of Orthopaedic Surgery, working on a variety of cartilage tissue engineering and mechano-biology projects. Patel has published over 20 manuscripts, has presented at numerous international conference meetings, and won several prestigious awards, including the Excellence in Research Award (2018) from the American Orthopaedic Society for Sports Medicine. Moreover, both his graduate and postdoctoral work resulted in pending patent applications, and the formation of startup companies with active small-business funding, demonstrating his ultimate goal of translating these approaches to the clinic.
 

Assistant Professor
Office
Emory MSK Institute, 6th Floor, Office 02
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience

John Oshinski

John Oshinski
jnoshin@emory.edu

Dr. Oshinski is known for his efforts at advancing the collaboration between Emory University and the Georgia Institute of Technology, as well as his dedication to advancing the technologies of MR imaging. He received his undergraduate degree from Kalamazoo College and BS, MS, and PhD from Georgia Institute of Technology. The underlying mission of his research is the application of engineering principles and technical problem-solving techniques to current clinical problems in the imaging, diagnosis, and treatment of cardiovascular disease. His research has concentrated on developing imaging applications that directly impact disease diagnosis and patient care.

Professor, Emory/Georgia Tech Department of Biomedical Engineering
Interim Director, Center for Systems Imaging
Phone
404-727-5894
IRI and Role
Bioengineering and Bioscience > Faculty
Bioengineering and Bioscience
University, College, and School/Department
Emory University > Department of Radiology and Imaging Sciences